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452483

Sigma-Aldrich

1-Methyl-D-tryptophan

95%, for peptide synthesis

Sinonimo/i:

(2R)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid, D-(+)-1-Methyltryptophan

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250 MG
46,10 €
1 G
124,00 €
10 G
905,00 €

46,10 €


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Cambia visualizzazione
250 MG
46,10 €
1 G
124,00 €
10 G
905,00 €

About This Item

Formula empirica (notazione di Hill):
C12H14N2O2
Numero CAS:
Peso molecolare:
218.25
Numero MDL:
Codice UNSPSC:
12352209
ID PubChem:
NACRES:
NA.22

46,10 €


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Nome del prodotto

1-Methyl-D-tryptophan, 95%

Livello qualitativo

Saggio

95%

Stato

lumps and powder

Attività ottica

[α]22/D +12.4°, c = 2 in acetic acid

Impiego in reazioni chimiche

reaction type: solution phase peptide synthesis

Punto di fusione

242-245 °C (lit.)

applicazioni

peptide synthesis

Stringa SMILE

Cn1cc(C[C@@H](N)C(O)=O)c2ccccc12

InChI

1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)/t10-/m1/s1
ZADWXFSZEAPBJS-SNVBAGLBSA-N

Applicazioni

Used to prepare a number of natural products including macroline alkaloids using the Pictet-Spengler reaction of tryptophan esters with aldehydes[1] also used in the synthesis of 1-substituted indolactam precursors.[2]

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

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Domande

1–5 di 5 domande  
  1. I have a question regarding 1-methyl-D-tryptophan (452483). Is this suitable for cell culture study purpose? Thank you.

    1 risposta
    1. This product is listed as suitable for peptide synthesis. It may be okay for cell culture, but it is not tested with that application in mind, so the suitability would need to be determined by the end user. What is tested can be found on the product COA, an example of which can be found in the 'Documentation' section of the product page.

      Utile?

  2. What is Product 452483, 1-Methyl-D-tryptophan, soluble in?

    1 risposta
    1. While we don't test the solubility of this product directly, we do have to dissolve it in acetic acid in order to test the optical rotation. We would also expect this to be soluble in a dilute hydrochloric acid solution (50mg/mL in 5N HCl). Both heat and sonication may be required in order to prepare a homogenous solution. Also, based on our experience with the DL (Product No. 860646) and L (Product No. 447439) forms, we would expect that dilute sodium hydroxide would also be a potential solvent (1g/100mL of 1M NaOH).

      Utile?

  3. What is the solution stability of Product 452483, 1-Methyl-D-tryptophan?

    1 risposta
    1. Unfortunately, we do not perform solution stability testing on this item or have experience with storing tryptophan solutions, so we would recommend making a fresh batch with each use.

      Utile?

  4. What is the Department of Transportation shipping information for this product?

    1 risposta
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Utile?

  5. How should Product 452483, 1-Methyl-D-tryptophan, be stored?

    1 risposta
    1. This material is stable at room temperature without any special handling precautions.

      Utile?

Recensioni

Nessuna valutazione

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