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Documenti fondamentali

296880

Sigma-Aldrich

4-Methoxymandelic acid

98%

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About This Item

Formula condensata:
CH3OC6H4CH(OH)CO2H
Numero CAS:
Peso molecolare:
182.17
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22

Saggio

98%

Stato

solid

Punto di fusione

108-111 °C (lit.)

Stringa SMILE

COc1ccc(cc1)C(O)C(O)=O

InChI

1S/C9H10O4/c1-13-7-4-2-6(3-5-7)8(10)9(11)12/h2-5,8,10H,1H3,(H,11,12)
ITECRQOOEQWFPE-UHFFFAOYSA-N

Descrizione generale

Chiral separation of the enantiomers of 4-methoxymandelic acid has been reported by a new liquid chromatographic method[1]. The mechanism of veratryl alcohol-mediated oxidation of 4-methoxymandelic acid by lignin peroxidase has been studied by kinetic methods[2].

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Radical cation cofactors in lignin peroxidase catalysis.
P J Harvey et al.
Biochemical Society transactions, 23(2), 262-267 (1995-05-01)
M Tien et al.
The Journal of biological chemistry, 272(14), 8912-8917 (1997-04-04)
The mechanism of veratryl alcohol-mediated oxidation of 4-methoxymandelic acid by lignin peroxidase was studied by kinetic methods. For monomethoxylated substrates not directly oxidized by lignin peroxidase, veratryl alcohol has been proposed to act as a redox mediator. Our previous study
L P Candeias et al.
The Journal of biological chemistry, 270(28), 16745-16748 (1995-07-14)
The formation and decay of veratryl alcohol radical cation upon oxidation of veratryl alcohol by thallium (II) ions was studied by pulse radiolysis with spectrophotometric and conductometric detection. In aqueous solution at pH 3 the radical cation decays by a
P J Teunissen et al.
FEBS letters, 439(3), 219-223 (1998-12-09)
Poly R478, 4-methoxymandelic acid and oxalic acid were oxidized by lignin peroxidase (LiP) in the presence of the fungal metabolite 2-chloro-1,4-dimethoxybenzene (2Cl-14DMB), whereas no oxidation occurred in the absence of 2Cl-14DMB. These substrates clearly inhibited the consumption of 2Cl-14DMB and
Jie Zhou et al.
Journal of Zhejiang University. Science. B, 14(7), 615-620 (2013-07-05)
A new liquid chromatographic method has been developed for the chiral separation of the enantiomers of mandelic acid and their derivatives 2-chloromandelic acid, 4-hydroxymandelic acid, 4-methoxymandelic acid, and 3,4,5-trismethoxymandelic acid. The enantiomers were separated by a CHIRALPAK(®) IC (250 mm×4.6

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