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Sigma-Aldrich

3-Amino-1,2,4-triazine

97%

Sinonimo/i:

3-Amino-as-triazine, [1,2,4]Triazin-3-ylamine

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About This Item

Formula empirica (notazione di Hill):
C3H4N4
Numero CAS:
Peso molecolare:
96.09
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22

Saggio

97%

Punto di fusione

174-177 °C (lit.)

Stringa SMILE

Nc1nccnn1

InChI

1S/C3H4N4/c4-3-5-1-2-6-7-3/h1-2H,(H2,4,5,7)
MJIWQHRXSLOUJN-UHFFFAOYSA-N

Descrizione generale

3-amino-1,2,4-triazine (ATN) acts as a single molecular carbon nitride precursor during the preparation of mesoporous carbon nitride with high nitrogen content via polymerization. Additionally, it is also used in the synthesis of organometal complexes.

Applicazioni

  • Antitumor activity in pharmaceutical applications: A study reported the development of a new library of 3-Amino-1,2,4-Triazine derivatives as PDK1 inhibitors, showing significant antitumor activity against pancreatic ductal adenocarcinoma, indicating its potential in cancer therapeutics (Carbone et al., 2023).
  • Structural analysis in crystallography: The crystal structure and Hirshfeld surface analysis of a complex involving 3-Amino-1,2,4-triazine was detailed, providing insights into the molecular interactions and potential applications in materials science and coordination chemistry (Sangeetha et al., 2018).
  • Catalytic applications in NMR technology: 3-Amino-1,2,4-triazine was used in a study to achieve significant NMR polarization in water using the SABRE technique, demonstrating its role as a catalyst in enhancing NMR sensitivity and its utility in magnetic resonance imaging (Zeng et al., 2014).

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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Jirí Hanusek et al.
Organic & biomolecular chemistry, 5(3), 478-484 (2007-01-26)
Contrary to a previous report, the sulfurisation of phosphorus(III) derivatives by 3-amino-1,2,4-dithiazole-5-thione (xanthane hydride) does not yield carbon disulfide and cyanamide as the additional reaction products. The reaction of xanthane hydride with triphenyl phosphine or trimethyl phosphite yields triphenyl phosphine
Grant Abernethy et al.
Journal of chromatography. A, 1285, 165-167 (2013-03-12)
A rapid liquid chromatography-mass spectrometry method to detect 3-amino-1,2,4-triazine (ATZ) in milk was developed as part of a programme to set up methods for detecting the economically motivated adulteration of raw milk with nitrogen-containing compounds. When ATZ was added to
Copper (II) complexes of 3-amino-1, 2, 4-triazine and 2-aminopyrazine: Strategies for designing crystalline materials using coordination polymers
Li L, et al.
Inorganica chimica acta, 362, 3845-3852 (2009)
Selective sensing performance of mesoporous carbon nitride with a highly ordered porous structure prepared from 3-amino-1, 2, 4-triazine
Mane GP, et al.
Journal of Materials Chemistry, 8, 2913-2920 (2013)
P A Taheri et al.
The Journal of clinical investigation, 93(1), 147-154 (1994-01-01)
Ultrasonic probes were placed around dog femoral arteries to record blood flow. Hind paw scalding with boiling water (5 s) caused a marked increase in ipsilateral femoral blood flow that persisted for the 2-h observation period. Contralateral femoral blood flow

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