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Merck

KCNH1

potassium voltage-gated channel, subfamily H (eag-related), member 1

Sinonimi:
EAG, EAG1, Kv10.1, h-eag
Specie:
ID UniProtKB:
ID gene:
  • Human(3756) Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(16510) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • Rat(65198) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • cow(281881) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • chicken(421381) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • domestic cat(101093161) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • dog(490277) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • Horse(100051219) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • sheep(101120348) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • Domestic Rabbit(100340515) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • domestic guinea pig(100719620) potassium voltage-gated channel, subfamily H (eag-related), member 1
  • naked mole-rat(101706330) potassium voltage-gated channel, subfamily H (eag-related), member 1

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Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
Levofloxacin, 98.0-102.0% anhydrous basis (HPLC),
Specie
human
N-Desmethylclozapine, ,
Specie
human
Sparfloxacin, ≥98.0% (HPLC),
Specie
human
Trimethoprim, ≥98.5%,
Specie
human, rat
Trimethoprim, ≥99.0% (HPLC),
Specie
human, rat

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-KCNH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Anti-KCNH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-KCNH1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
Anti-Potassium Channel EAG-1 Antibody, Chemicon®, from rabbit,
Reattività con
rat
Applicazione
western blot
Anti-Potassium Channel Kv10.1 (EAG-1) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reattività con
human, mouse, rat
Applicazione
western blot

Small Molecule - Blocker

N° Catalogo
Descrizione
Specie
Nitrendipine, >95%, powder,
Specie
human, rat
Pimozide, ,
Specie
human, mouse, rat
Nifedipine, ≥98% (HPLC), powder,
Specie
rat, mouse, human
Quinidine, anhydrous,
Specie
mouse, human, rat
Quinidine, crystallized, ≥98.0% (dried material, NT),
Specie
mouse, human, rat