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Merck

DDC

dopa decarboxylase (aromatic L-amino acid decarboxylase)

Sinonimi:
AADC
Specie:
ID UniProtKB:
ID gene:
  • Human(1644) Summary: The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2011]
  • Mouse(13195) dopa decarboxylase
  • Rat(24311) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • Zebrafish(406651) dopa decarboxylase
  • fruit fly(35190) Dopa decarboxylase
  • chicken(420947) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • dog(606852) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • domestic cat(101082989) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • cow(280762) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • Horse(100052557) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • sheep(101106765) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • naked mole-rat(101697555) dopa decarboxylase (aromatic L-amino acid decarboxylase)
  • domestic guinea pig(100135516) dopa decarboxylase

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ELISA

N° Catalogo
Descrizione
Specie
Human Dopa Decarboxylase ELISA, for serum, plasma and cell culture supernatants,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-DDC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-DDC antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2962, purified immunoglobulin, buffered aqueous glycerol solution,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
Anti-DDC antibody produced in rabbit, affinity isolated antibody,
Reattività con
guinea pig, human, mouse, rat
Applicazione
western blot
Anti-Dopa Decarboxylase Antibody, Chemicon®, from rabbit,
Reattività con
canine, human, sheep
Applicazione
western blot
Anti-DDC antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Benserazide hydrochloride, ≥98% (HPLC), solid,
Specie
human
Carbidopa, United States Pharmacopeia (USP) Reference Standard,
Specie
human
S-(−)-Carbidopa, ≥98% (TLC), powder,
Specie
human
Benserazide for peak identification A, European Pharmacopoeia (EP) Reference Standard,
Specie
human
Carbidopa, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Ddc,
Specie
mouse