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AB136

Sigma-Aldrich

Anti-Dopa Decarboxylase Antibody

Chemicon®, from rabbit

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Purificato mediante

affinity chromatography

Reattività contro le specie

canine, sheep, human

Produttore/marchio commerciale

Chemicon®

tecniche

western blot: suitable

N° accesso UniProt

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... DDC(1644)

Specificità

DOPA Decarboxylase (DDC). Reacts with a single band of ~55 kDa by Western blot. Reacts best with human samples; reactivity low with rodent and rabbit species.

Immunogeno

Synthetic peptide from the N-terminal region of human DDC conjugated to KLH.

Applicazioni

Anti-Dopa Decarboxylase Antibody is an antibody against Dopa Decarboxylase for use in WB.
Immunoblotting: 1:1000

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Neuronal & Glial Markers

Stato fisico

Affinity-purified antibody. Liquid in 10 mM HEPES, pH 7.5, 150 mM NaCl, 100 μg/mL BSA and 50% glycerol.

Stoccaggio e stabilità

Maintain at -20 to -80°C in undiluted aliquots for up to six months after date of receipt. Store in a non-self-defrosting freezer. Avoid repeated freeze-thaw cycles.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1


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Intrarenal dopamine modulates progressive angiotensin II-mediated renal injury.
Yang, S; Yao, B; Zhou, Y; Yin, H; Zhang, MZ; Harris, RC
American Journal of Physiology: Renal Physiology null
Thamara E Osinga et al.
Neuroendocrinology, 101(4), 289-295 (2015-02-14)
Increased dopamine production may be a feature of head and neck paraganglioma (HNPGL). 18F-fluorodihydroxyphenylalanine positron emission tomography scintigraphy has a high sensitivity for detecting HNPGLs. These observations strongly suggest that HNPGLs have the capacity for L-3,4-dihydroxyphenylalanine uptake and conversion towards
Mohammad M Doroudchi et al.
Journal of neurochemistry, 93(3), 634-640 (2005-04-20)
Although L-DOPA is the drug of choice for Parkinson's disease, prolonged L-DOPA therapy results in decreased drug effectiveness and the appearance of motor complications. This may be due in part to the progressive loss of the enzyme, aromatic L-amino acid
Masahiro Nezu et al.
Endocrine journal, 69(6), 705-716 (2022-01-21)
In 2008, a familial noradrenergic pheochromocytoma (PCC) with a KIF1B germline mutation in exon 41 was reported in a 24-year-old female proband and her family. However, in 2020, the same research group reported that the cause of PCC in this
Agnieszka Ciesielska et al.
PloS one, 10(4), e0122708-e0122708 (2015-04-11)
Progressively blunted response to L-DOPA in Parkinson's disease (PD) is a critical factor that complicates long-term pharmacotherapy in view of the central importance of this drug in management of the PD-related motor disturbance. This phenomenon is likely due to progressive

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