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Merck

AGTR1

angiotensin II receptor, type 1

Sinonimi:
AG2S, AGTR1A, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, AT2R1A, AT2R1B, HAT1R
Specie:
ID UniProtKB:
ID gene:
  • Human(185) Summary: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]
  • naked mole-rat(101714068) angiotensin II receptor, type 1
  • Domestic Rabbit(100009164) angiotensin II receptor, type 1
  • domestic guinea pig(100192325) angiotensin II receptor, type 1
  • sheep(443107) angiotensin II receptor, type 1
  • dog(403836) angiotensin II receptor, type 1
  • chicken(396065) angiotensin II receptor, type 1
  • cow(281607) angiotensin II receptor, type 1
  • domestic cat(101082936) angiotensin II receptor, type 1

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Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
ProteoMass Angiotensin II MALDI-MS Standard, vial of 10 nmol,
Specie
human
[Val5]-Angiotensin II acetate salt hydrate, ≥95% (HPLC), powder,
Specie
mouse, human, rat
[Asn1, Val5]-Angiotensin II, ≥97% (HPLC),
Specie
mouse, human, rat

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
Telmisartan, ≥98% (HPLC), solid,
Specie
human
Valsartan, ≥98% (HPLC),
Specie
human
Valsartan, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Losartan Potassium, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Telmisartan, United States Pharmacopeia (USP) Reference Standard,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-AT1 Receptor Antibody, Chemicon®, from rabbit,
Reattività con
human, mouse, rat
Applicazione
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-AGTR1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-AGTR1 Antibody, clone 1I12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
bovine, canine, human, mouse, rat
Applicazione
affinity binding assay
immunocytochemistry

western blot
Anti-AGTR1 antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, guinea pig, human, mouse, rabbit, rat, sheep
Applicazione
western blot
Anti-AT1R/AGTR1 Antibody, clone 8W6G0, Rabbit Monoclonal, ,
Reattività con
human
Applicazione
western blot

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Captopril, ≥98% (HPLC), powder,
Specie
human, rat
2,2′:5′,2′′:5′′,2′′′-Quaterthiophene, 96%,
Specie
human, rat, mouse

Proteins

N° Catalogo
Descrizione
Specie
ChemiSCREEN Human Angiotensin II Receptor, Type I Membrane Preparation, Human AT1 GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human AGTR1,
Specie
human