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Merck

ADRB2

adrenoceptor beta 2, surface

Sinonimi:
ADRB2R, ADRBR, B2AR, BAR, BETA2AR
Specie:
ID UniProtKB:
ID gene:
  • Human(154) Summary: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11555) adrenergic receptor, beta 2
  • Rat(24176) adrenoceptor beta 2, surface
  • cow(281605) adrenergic, beta-2-, receptor, surface
  • Horse(100060659) adrenoceptor beta 2, surface
  • domestic cat(493767) adrenoceptor beta 2, surface
  • naked mole-rat(101708921) adrenoceptor beta 2, surface
  • domestic guinea pig(100722663) adrenoceptor beta 2, surface
  • dog(403910) adrenoceptor beta 2, surface
  • chicken(427623) adrenergic, beta-2-, receptor, surface
  • Domestic Rabbit(100340821) adrenoceptor beta 2, surface
  • sheep(100170320) adrenoceptor beta 2, surface

Custom & Knockdown Gene Products

Small Molecule - Agonist

Numero di prodotto
Descrizione
Specie
(−)-Isoproterenol hydrochloride, ,
Specie
human
Clenbuterol hydrochloride, ≥95%,
Specie
human
Salbutamol, ,
Specie
human
Formoterol fumarate dihydrate, >98% (HPLC),
Specie
human
Albuterol sulfate, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human

Small Molecule - Antagonist

Numero di prodotto
Descrizione
Specie
ICI 118,551 hydrochloride, ≥98% (HPLC), powder,
Specie
human
Propranolol hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Specie
human
Propranolol hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Nadolol, analytical standard,
Specie
human
Timolol maleate, United States Pharmacopeia (USP) Reference Standard,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-ADRB2 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence

western blot
Anti-β2-Adrenergic Receptor Antibody, clone 2B23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human
Applicazione
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-ADRB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-Adrenergic Receptor β2 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-phospho-Adrenergic Receptor B2 (pSer355+Ser356) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry

western blot

Small Molecule - Blocker

Numero di prodotto
Descrizione
Specie
Sotalol hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Sotalol hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Specie
human
(±)-Sotalol hydrochloride, ≥98% (TLC), powder,
Specie
human
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
Specie
human
Propafenone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human ADRB2,
Specie
human
MISSION® esiRNA, targeting mouse Adrb2,
Specie
mouse