Product G3632 potency specification is ≥590 units/mg or I.U. Gentamicin base per mg. For lot specific results, please review the Certificate of Analysis for that lot.
G3632
Gentamicina sulfate salt
potency: ≥590 I.U. Gentamicin base per mg
Sinónimos:
GM Sulfate, Gentamicin C
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About This Item
Número de CAS:
Número CE:
Número MDL:
Código UNSPSC:
51281651
eCl@ss:
42020823
ID de la sustancia en PubChem:
NACRES:
NA.76
En este momento no podemos mostrarle ni los precios ni la disponibilidad
Productos recomendados
origen biológico
Micromonospora purpurea
Nivel de calidad
Formulario
powder
potencia
≥590 I.U. Gentamicin base per mg
≥590 units/mg Gentamicin
condiciones de almacenamiento
(Tightly closed. Dry. )
concentración
50 μg/mL in H2O (is the recommended working concentration for eukaryotic cell culture)
color
white to off-white
espectro de actividad antibiótica
Gram-negative bacteria
Gram-positive bacteria
mycoplasma
Modo de acción
protein synthesis | interferes
temp. de almacenamiento
2-8°C
cadena SMILES
O=S(O)(O)=O.O[C@]1(C)[C@@H]([C@@H](O)[C@@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3O[C@@](CC[C@H]3N)([C@@H](C)NC)[H])[C@@H](N)C[C@H]2N)OC1)NC.O[C@]4(C)[C@@H]([C@@H](O)[C@@H](O[C@@H]5[C@@H](O)[C@H](O[C@H]6O[C@@](CC[C@H]6N)([C@@H](C)N)[H])[C@@H](N)C[C@H]5N)OC4)NC.O[
InChI
1S/C21H43N5O7.C20H41N5O7.C19H39N5O7.H2O4S/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20;1-8(21)12-5-4-9(22)18(30-12)31-15-10(23)6-11(24)16(13(15)26)32-19-14(27)17(25-3)20(2,28)7-29-19;1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;1-5(2,3)4/h9-20,25-29H,5-8,22-24H2,1-4H3;8-19,25-28H,4-7,21-24H2,1-3H3;8-18,24-27H,3-7,20-23H2,1-2H3;(H2,1,2,3,4)/t9-,10-,11+,12-,13+,14+,15-,16-,17+,18-,19-,20-,21+;8-,9-,10+,11-,12+,13+,14-,15-,16+,17-,18-,19-,20+;8-,9+,10-,11+,12-,13+,14+,15-,16+,17+,18+,19-;/m110./s1
Clave InChI
RDEIXVOBVLKYNT-HDZPSJEVSA-N
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Descripción general
Gentamicin sulfate Salt is a broad-spectrum aminoglycoside antibiotic which is derived from Micromonospora purpurea.
Aplicación
Gentamicin sulfate Salt is used as a selection agent (gentamicin-resistance gene) in cell culture and molecular biology applications. This product is recommended for use at 50 mg/L. Gentamicin sulfate Salt can be used:
Acciones bioquímicas o fisiológicas
Modo de acción: La gentamicina produce un error de lectura de codón al unirse a la subunidad ribosómica 30S y bloquear la translocación del peptidil-ARNt del sitio aceptor al sitio donante. El efecto bactericida de la gentamicina en Pseudomonas aeruginosa se ejerce mediante la unión de la gentamicina a la membrana externa, donde desplaza los cationes naturales, desestabiliza la membrana y forma agujeros en la superficie celular.
Espectro antimicrobiano: Incluye bacterias gramnegativas y grampositivas, entre ellas cepas resistentes a la tetraciclina, el cloranfenicol, la canamicina y la colistina, en particular cepas de Pseudomonas, Proteus, Staphylococcus y Streptococcus.
Espectro antimicrobiano: Incluye bacterias gramnegativas y grampositivas, entre ellas cepas resistentes a la tetraciclina, el cloranfenicol, la canamicina y la colistina, en particular cepas de Pseudomonas, Proteus, Staphylococcus y Streptococcus.
Características y beneficios
High quality antibiotic suitable for mulitple research applications
Componentes
Freely soluble in water, practically insoluble in ethanol
Gentamicin is an aminoglycoside complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is used as the sulfate salt. There are three components, each consisting of five basic nitrogens and requiresing five equivalents of sulfuric acid per mole of gentamicin base.
Almacenamiento y estabilidad
Sterile solutions should be stored at 2-8°C. Solutions have also been shown to be stable at room temperature and in boiling aqueous buffers of pH 2-14. [2]
Otras notas
For additional information on our range of Biochemicals, please complete this form.
producto comparable
Palabra de señalización
Warning
Frases de peligro
Consejos de prudencia
Clasificaciones de peligro
Skin Sens. 1
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 2
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Equipo de protección personal
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Certificados de análisis (COA)
Lot/Batch Number
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G3632の1g当たりの力価について教えて頂きたいです。
1 answer-
Helpful?
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Regarding the MQ Levels, can you please clarify the difference between "enhanced control" and increased control"
1 answer-
The difference between enhanced control and increased control, in reference to the M-Clarity program, is essentially a matter of degrees. The MQ 100 level products are intended for use in basic research and minimum control is applied to areas such as sourcing, testing method, and available documentation. With increasing MQ levels more rigid controls and guidelines are put in place for these products. The MQ 200 products have an 'increased' level of control while MQ 300 level products having 'enhanced' level of control. Considering the breadth of products offered the specific controls are subject to the nature of the product.
The link below offers a line-by-line listing of the various discriminating attributes that are considered 'controls'.
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/323/519/M-Clarity_attributes_table_ms.pdfHelpful?
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