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Solid-phase synthesis of C-terminal azapeptides.

Solid-phase synthesis of C-terminal azapeptides.

Journal of peptide science : an official publication of the European Peptide Society (2014-11-18)

Ngoc-Duc Doan, Jinqiang Zhang, Mariam Traoré, Winnie Kamdem, William D Lubell

摘要

The solid-phase synthesis of azapeptides possessing a C-terminal aza-residue has been accomplished by a protocol featuring regioselective alkylation of benzhydrylidene-aza-glycinamide and illustrated by the syntheses of [aza-Lys(6)] growth-hormone-releasing peptide-6 analogs.

材料

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