1327000

硫酸羟氯喹

United States Pharmacopeia (USP) Reference Standard

• 别名: 7-氯-4-[4-（N-乙基-N-b-羟乙基氨基）-1-甲基丁氨基] 喹啉硫酸盐
• 经验公式（希尔记法）: C₁₈H₂₆ClN₃O · H₂SO₄
• CAS号: 747-36-4
• 分子量: 433.95
• EC號碼: 212-019-3
• MDL號碼: MFCD00078203
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329750122
• NACRES: NA.24

属性

• 生物源: synthetic
• 等級: pharmaceutical primary standard
• agency: USP
• API 家族: hydroxychloroquine
• 包裝: pkg of 200 mg
• 製造商／商標名: USP
• 儲存條件: protect from light
• 顏色: white to off-white
• pH值: 3.5-5.5 (1% in aqueous solution, pH <6.0)
• mp: 388.4 °F (198°C; 240°C)
• 溶解度: chloroform: practically insoluble; ethanol: practically insoluble; ether: practically insoluble; water: soluble
• 應用: pharmaceutical (small molecule)
• 格式: neat
• SMILES 字串: OS(O)(=O)=O.CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12
• InChI: 1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)
• InChI 密鑰: JCBIVZZPXRZKTI-UHFFFAOYSA-N
• 基因資訊: human ... TLR7(51284) , TLR9(54106)

说明

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Hydroxychloroquine Sulfate is a salt of hydroxychloroquine (HCQ, Plaquenil), a 4-aminoquinoline based antiviral drug.

應用

Hydroxychloroquine sulfate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Hydroxychloroquine Sulfate Tablets
• Hydroxychloroquine Sulfate Compounded Oral Suspension
• Chloroquine Phosphate

生化／生理作用

硫酸羟氯喹是一种抗炎（通过肿瘤坏死因子）、疾病调节抗风湿药物（DMARD）和血红素聚合酶抑制剂。 它可用于治疗疟疾。

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302,H315,H319
• 防範說明: P301 + P312 + P330 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable