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Merck

55263-U

Supelco

Protein Precipitation Filter 96-well solid phase extraction (SPE) Plate

Volume 2 mL, pk of 1

别名:

Protein Precipitation Plate

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About This Item

分類程式碼代碼:
41115712
NACRES:
NB.21

product name

96 孔蛋白质沉淀过滤板, pk of 1

包裝

pk of 1

技術

solid phase extraction (SPE): suitable

容積

2 mL

一般說明

96孔蛋白质沉淀滤板是去除生物血浆/血清中沉淀蛋白质的理想设备。该板由0.2 μm疏水层级过滤器/熔块组成。 首先将生物血浆加入96孔板,然后加入蛋白质沉淀剂(例如乙腈)。经过短暂的混合步骤后,向平板施加真空,过滤器/熔块从样品中去除沉淀的蛋白质。 所得滤液可用于进一步处理和/或分析。

應用


  • Determination of estrone sulfate, testosterone, androstenedione, DHEAS, cortisol, cortisone, and 17α-hydroxyprogesterone by LC-MS/MS in children and adolescents.: This study employs 96-Well Protein Precipitation Filter Plates for rapid sample preparation, significantly increasing the throughput of hormone analysis in pediatric populations. This technique enhances the accuracy and efficiency of hormonal assessments, crucial for clinical and research settings (Ankarberg-Lindgren et al., 2020).

  • Quantitative Determination of Ethyl Glucuronide and Ethyl Sulfate in Postmortem and Antemortem Whole Blood Using Phospholipid Removal 96-Well Plate and UHPLC-MS-MS.: This research demonstrates the utility of 96-Well Filter Plates in removing phospholipids from blood samples, streamlining the detection of ethyl glucuronide and ethyl sulfate, substances important for forensic and clinical toxicology (Sidqey et al., 2021).

  • Development of a CDC-certified total testosterone assay for adult and pediatric samples using LC-MS/MS.: The study highlights the application of 96-Well Protein Precipitation Filter Plates in developing a CDC-certified assay for testosterone, showing their critical role in enhancing diagnostic accuracy in clinical settings (Star-Weinstock et al., 2019).

  • Validation and application of a liquid chromatography-tandem mass spectrometric method for quantification of the drug transport probe fexofenadine in human plasma using 96-well filter plates.: This paper validates a high-throughput method for the analysis of fexofenadine, showcasing the 96-Well Filter Plates′ efficiency in clinical pharmacology and bioanalysis settings (Stanton et al., 2010).


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Miau-Guo Kang et al.
Journal of analytical toxicology, 43(2), 96-103 (2018-10-03)
Benzodiazepines is a large drug group used extensively to treat sleep disorders and anxiety; these drugs are frequently associated with various crimes such as murder and drug-facilitated sexual assault. With growing use and misuse of these compounds, confirmatory assays are

商品

An article focusing on ion-suppression and phospholipid contamination and some of their major causes and difficulties.

This Sigma-Aldrich article discusses how the HybridSPE-Phospholipid Technology works and how the phospholipids are removed.

This article highlights the impact that sample matrix effects can have on LC/MS response and discusses two novel approaches to reduce it.

实验方案

A simple method to enrich phospholipids from plasma samples, involving a HybridSPE-PPT 96-well plate that both retains phospholipids and removes precipitated proteins.

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