所有图片(1)
About This Item
经验公式（希尔记法）:
C11H17N3O8
CAS号:
分子量:
319.27
Beilstein:
49176
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
推荐产品
形狀
powder
存貨情形
not available in USA
pH值
4.8
溶解度
H2O: soluble (stable at pH 4-5 if stored frozen)
strong acid or alkaline solutions: unstable (destroyed by boiling at pH 2.)
儲存溫度
2-8°C
SMILES 字串
OC[C@@]1(O)[C@H]2OC3(O)OC1C4[C@@H](O)NC(=N)NC4([C@@H]2O)[C@@H]3O
InChI
1S/C11H17N3O8/c12-8-13-6(17)2-4-9(19,1-15)5-3(16)10(2,14-8)7(18)11(20,21-4)22-5/h2-7,15-20H,1H2,(H3,12,13,14)/t2?,3-,4?,5+,6-,7+,9+,10?,11?/m1/s1
InChI 密鑰
CFMYXEVWODSLAX-IXUBDLNJSA-N
基因資訊
rat ... Scnn1g(24768)
應用
Tetrodotoxin has been used to study its effects on microglial functions in rats2. This toxin has also been used to inactivate lateral magnocellular nucleus of the nidopallium (LMAN) in juvenile zebra finch. This study reported that the toxin causes a decrease in sequence and acoustic variability which result in the production of a stereotyped song by the motor pathway3.
生化／生理作用
Reversible, selective blocker of Na+ channels; blocks propagation of impulses in excitable membranes. Used to characterize sodium channels in excitable membranes and to study the role of sodium channels in normal physiology and disease.
包裝
Vial contains 1 mg of tetrodotoxin and approx. 5 mg citrate buffer, pH 4.8.
準備報告
The product is water soluble and stable at pH 4-5 if it is stored frozen. It is unstable in strong acid and alkaline solutions and is rapidly destroyed by boiling at pH 2 and below.
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 1 Oral
儲存類別代碼
6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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