跳转至内容
Merck
所有图片(1)

文件

T1567

Sigma-Aldrich

Tertiapin-Q trifluoroacetate salt

≥97% (HPLC)

别名:

[Gln13]-Tertiapin, Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-His-Gln-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH2 [Disulfide bridges 3–14, 5–18], TPNQ

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C106H175N35O24S4
CAS号:
910044-56-3
分子量:
2452.00
MDL號碼:
MFCD02684419
分類程式碼代碼:
12352200
NACRES:
NA.32

品質等級

200

化驗

≥97% (HPLC)

形狀

lyophilized

儲存溫度

−20°C

基因資訊

human ... KCNJ1(3758)
mouse ... KCNJ1(56379)
rat ... KCNJ1(24521)

相关类别

Amino Acid Sequence

Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-His-Gln-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH2 [Disulfide bridges 3–14, 5–18]

生化／生理作用

Blocks the GIRK1/4 and ROMK1 members of the inward-rectifier K+ channel family.

其他說明

Non-air oxidizable tertiapin derivative.
Lyophilized from 0.1% TFA in H2O

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

W Jin et al.
Biochemistry, 38(43), 14286-14293 (1999-11-26)
Tertiapin (TPN), a small protein derived from honey bee venom, inhibits the GIRK1/4 and ROMK1 channels with nanomolar affinities. Methionine residue 13 in TPN interacts with residue F148 in the channel, located just outside of the narrow region of the
W Jin et al.
Biochemistry, 38(43), 14294-14301 (1999-11-26)
Tertiapin-Q (TPN(Q)) is a derivative of honey bee toxin tertiapin (TPN) whose methionine residue is replaced with a glutamine residue. TPN(Q) inhibits the ROMK1 and GIRK1/4 inward-rectifier K(+) channels with affinities very similar to TPN. However, unlike native TPN, TPN(Q)
W Jin et al.
Biochemistry, 37(38), 13291-13299 (1998-09-28)
Inward-rectifier K+ channels are a group of highly specialized K+ channels that accomplish a variety of important biological tasks. Inward-rectifier K+ channels differ from voltage-activated K+ channels not only functionally but also structurally. Each of the four subunits of the

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门