SRP8035

IL-36α mouse

>95% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized

• 别名: Interleukin-1 family member 6, Interleukin-1 homolog 1, Interleukin-1α, Interleukin-36α
• UNSPSC代码: 12352202
• NACRES: NA.32

属性

• 产品名称: IL-36α mouse, recombinant, expressed in E. coli, untagged, >95% (SDS-PAGE)
• 生物来源: mouse
• 重组: expressed in E. coli
• 偶联物: untagged
• 方案: >95% (SDS-PAGE)
• 表单: lyophilized
• 分子量: ~17 kDa
• 包装: pkg of 10 μg
• 杂质: <0.01 EU/μg endotoxin, tested
• UniProt登记号: Q9JLA2
• 运输: wet ice
• 储存温度: −20°C
• 基因信息: mouse ... Il36a(54448)

说明

一般描述

IL-36α (IL-1F6), IL-36β (IL-1F8) and IL-36γ (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1β, IL-6, TNF-α and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.

外形

Lyophilized from PBS.

重悬

Reconstitute with 100 μL deionized water.

其他说明

IL-36alpha (mouse) (aa 8-160) is untagged.

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 2
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable