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质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: 2 mg/mL, clear
储存温度
2-8°C
SMILES字符串
O=C1C2=CC=C(C=C2OC=C1C3=CC4=C(C=C3)OC(C)(C)C=C4)O
InChI key
PWAACAMQKVIVPZ-UHFFFAOYSA-N
生化/生理作用
Corylin is a flavonoid isolated from fruit and seed of medical herb Psoralea corylifolia that extend the replicative lifespan in yeast by targeting the Gtr1 protein. Also, Corylin extends lifespan in mice fed a high-fat diet. Corylin exhibits numerous pharmacological effects such as antioxidant properties, anti-inflammatory effects, osteoblastic proliferation-stimulating activity, insulin resistance amelioration.
Extend the replicative lifespan in yeast by targeting the Gtr1 protein
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
I-Chen Chen et al.
Pharmaceuticals (Basel, Switzerland), 14(10) (2021-10-24)
Acute lung injury (ALI) is a high mortality disease with acute inflammation. Corylin is a compound isolated from the whole plant of Psoralea corylifolia L. and has been reported to have anti-inflammatory activities. Herein, we investigated the therapeutic potential of
Zi-Yu Chang et al.
International journal of molecular sciences, 23(5) (2022-03-11)
Inflammatory bowel disease (IBD) involves chronic inflammation, loss of epithelial integrity, and gastrointestinal microbiota dysbiosis, resulting in the development of a colon cancer known as colitis-associated colorectal cancer (CAC). In this study, we evaluated the effects of corylin in a
Tong-Hong Wang et al.
Nature communications, 13(1), 1238-1238 (2022-03-11)
In the long history of traditional Chinese medicine, single herbs and complex formulas have been suggested to increase lifespan. However, the identification of single molecules responsible for lifespan extension has been challenging. Here, we collected a list of traditional Chinese
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