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表单
powder
颜色
off-white
溶解性
water: 1 mg/mL, clear to slightly hazy
抗生素抗菌谱
Gram-negative bacteria
Gram-positive bacteria
作用机制
enzyme | inhibits
储存温度
2-8°C
一般描述
Material is a powdered mixture of 1 part potassium clavulanate to 1 part silicon dioxide.
生化/生理作用
Clavulanate is a β-lactam antibiotic related to the penicillins. Clavulanate competitively and irreversibly inhibits a wide variety of β-lactamases found in bacteria that are resistant to penicillins and cephalosporins.
包装
1G
储存及稳定性
Keep container tightly closed in a dry and well-ventilated place. Never allow produc to get in contact with water during storage.
其他说明
Keep container tightly closed in a dry and well-ventilated place. Never allow product to get in contact with water during storage.
警示用语:
Danger
危险分类
Resp. Sens. 1 - Self-heat. 2 - Skin Sens. 1 - STOT RE 1 Inhalation
靶器官
Lungs
补充剂危害
储存分类代码
4.2 - Pyrophoric and self-heating hazardous materials
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
B G Spratt et al.
Antimicrobial agents and chemotherapy, 12(3), 406-409 (1977-09-01)
Thienamycin and clavulanic acid are new beta-lactam derivatives with structures markedly different from those of penicillins or cephalosporins. Both derivatives had the same general mode of action as typical beta-lactam antibiotics since they bound to precisely the same proteins as
C Reading et al.
Antimicrobial agents and chemotherapy, 11(5), 852-857 (1977-05-01)
A novel beta-lactamase inhibitor has been isolated from Streptomyces clavuligerus ATCC 27064 and given the name clavulanic acid. Conditions for the cultivation of the organism and detection and isolation of clavulanic acid are described. This compound resembles the nucleus of
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