SAB5702340

Anti-Thyroglobulin Antibody, clone 3I10H1, Rabbit Monoclonal

• 别名: AITD3, TGN
• 分類程式碼代碼: 12352203
• NACRES: NA.46

属性

• 生物源: rabbit
• 品質等級: 100
• 材料: colorless
• 無性繁殖: 3I10H1, monoclonal
• 形狀: liquid
• 物種活性: human, rat, rat
• 濃度: 0.70 mg/mL
• 技術: immunofluorescence: 1:50 - 1:200; immunohistochemistry: 1:50 - 1:200
• 顏色: colorless
• 同型: IgG
• 免疫原序列: STLSFYQRRRFSPDDSAGASALLRSGPYMPQCDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGSLTARSLQIPQCPTTCEKSRTSGLLSSWKQARSQENPSP
• UniProt登錄號: P01266
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... TG(7038)

说明

一般說明

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1000-1100 of human Thyroglobulin (P01266).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

IHC, IF/ICC

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1