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生物来源
synthetic (Organic)
方案
≥99%
表单
powder
颜色
white to off-white
溶解性
H2O: soluble 50 mg/mL
抗生素抗菌谱
Gram-negative bacteria
Gram-positive bacteria
mycoplasma
作用机制
DNA synthesis | interferes
enzyme | inhibits
SMILES字符串
Nc1ccc(cc1)S(=O)(=O)N([Na])c2nccs2
InChI
1S/C9H8N3O2S2.Na/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9;/h1-6H,10H2;/q-1;+1
InChI key
GWIJGCIVKLITQK-UHFFFAOYSA-N
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一般描述
化学结构：磺胺
应用
磺胺噻唑是一种短效磺胺药。在发现毒性较低的替代品之前，它是一种常见的口服和外用抗生素。它不再用于人类。在实验动物的饮食中加入磺胺噻唑可抑制肠道细菌形成叶酸。这确保了动物可用叶酸的唯一来源是它们的饮食。
生化/生理作用
磺胺噻唑是一种磺胺类抗生素，通过抑制二氢丙酸合成酶来阻断二氢叶酸的合成。磺胺噻唑是细菌对氨基苯甲酸（PABA）的竞争性抑制剂，它是细菌合成叶酸所必需的。它对革兰氏阳性细菌、革兰氏阴性细菌和衣原体均具有抗性。抗性产生机制是通过改变二氢蝶酸合成酶或叶酸合成的替代途径。
其他说明
保存于密闭容器内，置于干燥通风处。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 2
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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