N1415

Naratriptan hydrochloride

≥98% (HPLC)

• 别名: Amerge, GR-85548A, N-Methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide hydrochloride
• 经验公式（希尔记法）: C₁₇H₂₅N₃O₂S ·HCl
• CAS号: 143388-64-1
• 分子量: 371.93
• MDL號碼: MFCD08141821
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329818579
• NACRES: NA.77

属性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to off-white
• 溶解度: H₂O: ≥10 mg/mL
• 起源: GlaxoSmithKline
• 儲存溫度: room temp
• SMILES 字串: Cl.CNS(=O)(=O)CCc1ccc2[nH]cc(C3CCN(C)CC3)c2c1
• InChI: 1S/C17H25N3O2S.ClH/c1-18-23(21,22)10-7-13-3-4-17-15(11-13)16(12-19-17)14-5-8-20(2)9-6-14;/h3-4,11-12,14,18-19H,5-10H2,1-2H3;1H
• InChI 密鑰: AWEZYKMQFAUBTD-UHFFFAOYSA-N
• 基因資訊: human ... HTR1B(3351) , HTR1D(3352)

说明

生化／生理作用

Naratriptan hydrochloride is a triptan drug that is used to relieve acute migraine headaches. It has poor bioavailability, short half-life, and the incidence of migraine recurrence therefore, it is occasionally used.

Naratriptan hydrochloride is a serotonin 5-HT_1B/1D receptor agonist.

特點和優勢

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H319
• 防範說明: P264 - P280 - P305 + P351 + P338 - P337 + P313
• 危險分類: Eye Irrit. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable