N1040
N1-(7-硝基-2,1,3-苯并噁二唑-4-基)-N1,N2,N2-顺式(2-吡啶基甲基)-1,2-乙二胺
for fluorescence
别名:
N-(2-(Bis((pyridin-2-yl)methyl)amino)ethyl)-7-nitro-N-((pyridin-2-yl)methyl)benzo[c][1,2,5]oxadiazole-4-amine, NBD-TPEA
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所有图片(1)
About This Item
经验公式（希尔记法）:
C26H24N8O3
CAS号:
分子量:
496.52
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
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等級
for fluorescence
化驗
≥95%
形狀
solid
螢光
λex 470 nm; λem 534 nm
運輸包裝
wet ice
儲存溫度
−20°C
SMILES 字串
[O-][N+](=O)c1ccc(N(CCN(Cc2ccccn2)Cc3ccccn3)Cc4ccccn4)c5nonc15
InChI
1S/C26H24N8O3/c35-34(36)24-11-10-23(25-26(24)31-37-30-25)33(19-22-9-3-6-14-29-22)16-15-32(17-20-7-1-4-12-27-20)18-21-8-2-5-13-28-21/h1-14H,15-19H2
InChI 密鑰
WBROPDACWHVGSC-UHFFFAOYSA-N
應用
N1-(7-Nitro-2,1,3-benzoxadiazol-4-yl)-N1,N2,N2-tris(2-pyridinylmethyl)-1,2-ethanediamine has a high sensitivity for zinc ions. Using fluorescent detection, a linear responsive is observed for Zn2+ concentrations in the range of 1-10 μM. It has good selectivity for Zn2+ in the presence of competing metal ions, such as Ca2+, Mg2+, Fe2+, Fe3+, and Mn2+, and has been used in vivo to determine Zn2+ concentration in pancreatic β cells and zebra fish larvae.
訊號詞
Danger
危險分類
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Sandip Nathani et al.
Journal of fluorescence, 30(6), 1553-1565 (2020-09-19)
Zinc is essential for growth and development of all living organisms, especially human being. Deficiency of micronutrients like zinc and iron has been linked to the manifestation of hidden hunger. Therefore, it is imperative that development of some rapid screening
Nabil Hanna et al.
mBio, 12(1) (2021-02-04)
Macrophages use diverse strategies to restrict intracellular pathogens, including either depriving the bacteria of (micro)nutrients such as transition metals or intoxicating them via metal accumulation. Little is known about the chemical warfare between Mycobacterium marinum, a close relative of Mycobacterium
Tianke Zhang et al.
International journal of nanomedicine, 15, 1457-1468 (2020-03-19)
Zinc oxide nanoparticles (nZnO) have been widely used in the medicine field. Numerous mechanistic studies for nZnO's anticancer effects are merely performed under high concentration exposure. However, possible anticancer mechanisms of epigenetic dysregulation induced by low doses of nZnO are
Caroline Barisch et al.
Journal of cell science, 131(23) (2018-11-09)
Professional phagocytes have developed an extensive repertoire of autonomous immunity strategies to ensure killing of bacteria. Besides phagosome acidification and the generation of reactive oxygen species, deprivation of nutrients and the lumenal accumulation of toxic metals are essential to kill
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