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About This Item
经验公式（希尔记法）:
C6H2ClN3O3
CAS号:
分子量:
199.55
Beilstein:
614212
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
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化驗
98%
形狀
powder
mp
97-99 °C (lit.)
溶解度
chloroform: soluble 50 mg/mL, clear to slightly hazy, faintly yellow to yellow
SMILES 字串
[O-][N+](=O)c1ccc(Cl)c2nonc12
InChI
1S/C6H2ClN3O3/c7-3-1-2-4(10(11)12)6-5(3)8-13-9-6/h1-2H
InChI 密鑰
IGHBXJSNZCFXNK-UHFFFAOYSA-N
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一般說明
4-氯-7-硝基苯并呋喃（NBD-Cl）是一种高度灵敏的发色和荧光试剂。据报道，它能与 反-1-甲氧基-3-(三甲基硅氧基)-1,3-丁二烯（Danishefsky二烯）发生自发反应，通过正常电子需求的Diels-Alder（NEDDA）反应，区域选择性地生成烯醇硅醚。已有研究对NBD-Cl进行了分子结构、振动光谱和NBO（自然键轨道）分析。它作为柱前衍生剂的用途已被研究。
應用
4-氯-7-硝基苯并呋喃（NBD-氯化物）被用于以下研究：
- 合成荧光磷脂衍生物，即NBD-二癸酰基磷脂酰乙醇胺
- 合成官能化羟基萘并呋咱。
- 药物配方中富马酸氯马斯汀、氯雷他定、氯沙坦钾和雷米普利的分光光度法和荧光分光光度法测定。
- 通过Diels-Alder反应合成7-硝基苯并呋喃（NBD）-标记的马来酰亚胺。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
個人防護裝備
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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商品
The Diels–Alder reaction is the reaction between a conjugated diene and an alkene (dienophile) to form unsaturated six-membered rings. It is also referred to as a cycloaddition.
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