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品質等級
應用
pharmaceutical
檢測方法
fluorometric
相關疾病
cancer; neurological disorders; gastrointestinal diseases; genitourinary disorders
運輸包裝
wet ice
儲存溫度
−20°C
一般說明
Alkaline phosphatase (ALP) catalyzes the hydrolysis of phosphate esters in an alkaline environment, resulting in the formation of an organic radical and inorganic phosphate. In mammals, this enzyme is found mainly in the liver and bones. Marked increase in serum ALP levels, a disease known as hyperalkalinephosphatasemia, has been associated with malignant biliary obstruction, primary biliary cirrhosis, primary sclerosing cholangitis, hepatic lymphoma and sarcoidosis.
特點和優勢
- Detection limit of 0.02 U/L
- Compatible with high-throughput handling systems.
適合性
The kit is suitable for ALP activity in serum, plasma and other sources, characterization and quality control for ALP production, and for high-throughput screening for ALP modulators.
原則
The Alkaline Phosphatase (ALP) Assay Kit utilizes 4-methylumbelliferyl phosphate that is hydrolyzed by ALP into the highly fluorescent product 4methylumbelliferone. The rate of the fluorescence increase is directly proportional to the enzyme activity.
訊號詞
Danger
危險聲明
危險分類
Eye Dam. 1
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 1
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