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用途
sufficient for 100 colorimetric tests
檢測方法
colorimetric
相關疾病
cancer; cardiovascular diseases; hematological disorder
儲存溫度
−20°C
基因資訊
human ... MPO(4353)
mouse ... MPO(17523)
rat ... MPO(303413)
一般說明
髓过氧化物酶(MPO)是一种含血红素的酶,催化氢过氧化物酶介导的卤离子氧化为次氯酸。髓过氧化物酶是一种在中性粒细胞中高度表达的溶酶体蛋白,其在由中性粒细胞刺激引起的抗微生物作用中起作用。髓过氧化物酶的作用也可能有助于心血管疾病的发生和发病。
應用
髓过氧化物酶比色活性测定试剂盒已用于测定样品中髓过氧化物酶的活性。
特點和優勢
兼容高通量处理系统。
適合性
适用于组织、细胞、血清和白细胞等生物样本中髓过氧化物酶 (MPO) 的测定
原則
在该测定中,髓过氧化物酶催化次氯酸的形成,次氯酸与牛磺酸反应形成牛磺酸氯胺。牛磺酸氯胺与发色团 TNB 反应,形成无色产物 DTNB。一个单位的髓过氧化物酶活性定义为在 25℃ 下,每分钟水解底物并产生牛磺酸氯胺以消耗 1.0 μmole TNB的酶量。
訊號詞
Danger
危險分類
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1
儲存類別代碼
10 - Combustible liquids
閃點(°F)
188.6 °F
閃點(°C)
87 °C
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