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Merck

M2398

Sigma-Aldrich

Metaproterenol hemisulfate salt

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About This Item

线性分子式:
C11H17NO3 · 1/2H2SO4
CAS号:
分子量:
260.30
EC號碼:
MDL號碼:
分類程式碼代碼:
12352107
PubChem物質ID:
NACRES:
NA.77

品質等級

起源

Boehringer Ingelheim

SMILES 字串

OS(O)(=O)=O.CC(C)NCC(O)c1cc(O)cc(O)c1.CC(C)NCC(O)c2cc(O)cc(O)c2

InChI

1S/2C11H17NO3.H2O4S/c2*1-7(2)12-6-11(15)8-3-9(13)5-10(14)4-8;1-5(2,3)4/h2*3-5,7,11-15H,6H2,1-2H3;(H2,1,2,3,4)

InChI 密鑰

MKFFGUZYVNDHIH-UHFFFAOYSA-N

基因資訊

human ... ADRB2(154)

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應用

Metaproterenol hemisulfate salt has been used:
  • as a β2-adrenoceptor agonist to study its effects on adenylyl cyclase stimulation in red blood cell deformability
  • as an adrenergic agonist to study its effects on the stereoselective cell uptake by organic cation transporters in human embryonic kidney cell lines
  • as a bronchodilator to study its effects on the activation of G-protein coupled receptors (GPCR)

生化/生理作用

Metaproterenol is a β2-adrenoceptor agonist. It shows bronchodilator activity and shows therapeutic effects against bronchitis, asthma, and emphysema.

特點和優勢

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Inhalation

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Stimulation by transforming growth factor-α of DNA synthesis and proliferation of adult rat hepatocytes in primary cultures: modulation by α- and β-adrenoceptor agonists.
Kimura, M., et al.
Journal of Pharmacology and Experimental Therapeutics, 29, 171-171 (1999)
A M Krumins et al.
Biochemical pharmacology, 54(1), 61-72 (1997-07-01)
We have examined the effect of increased Gs protein levels on the abilities of three different beta2-agonists to induce GTP shifts and stimulate adenylyl cyclase response in an effort to investigate the kinetic association between the beta2-adrenergic receptor Gs and
Simona Codruţa Cobzac et al.
Journal of chromatographic science, 52(9), 1095-1103 (2013-10-29)
The retention behavior for a series of amine neurotransmitters, their precursors, metabolites and structurally related drugs has been investigated in reversed-phase thin-layer chromatography using RP-18, RP-8, RP-2, CN and Diol stationary phases and mixtures of phosphate buffer and methanol as

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