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Merck

L8783

Sigma-Aldrich

α-乳糖 一水合物

≥99% total lactose basis (GC), BioXtra

别名:

β-D-Gal-(1→4)-α-D-Glc, 4-O-β- D -半乳糖基-α- D -葡萄糖, 乳糖

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About This Item

经验公式(希尔记法):
C12H22O11 · H2O
CAS号:
分子量:
360.31
MDL號碼:
分類程式碼代碼:
12352201
PubChem物質ID:
NACRES:
NA.25

生物源

bovine milk

產品線

BioXtra

化驗

≥99% total lactose basis (GC)

形狀

powder

雜質

≤0.01% Phosphorus (P)
≤0.1% Insoluble matter

燃燒殘留物

≤0.1%

顏色

white to off-white

mp

219  °C ((426 °F ))

溶解度

H2O: 1 M, clear, colorless

負離子痕跡

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%

正離子痕跡

Al: ≤0.0005%
Ca: ≤0.005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.02%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

SMILES 字串

[H]O[H].OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C12H22O11.H2O/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17;/h3-20H,1-2H2;1H2/t3-,4-,5+,6+,7-,8-,9-,10-,11+,12+;/m1./s1

InChI 密鑰

WSVLPVUVIUVCRA-KPKNDVKVSA-N

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應用


  • Insights into the potential of rheological measurements in development of dry powder inhalation formulations.: This article investigates rheological properties and their implications in the development of inhalation formulas where a-Lactose monohydrate plays a crucial role (Almansour et al., 2022).

  • Spray-Congealing and Wet-Sieving as Alternative Processes for Engineering of Inhalation Carrier Particles: Comparison of Surface Properties, Blending and In Vitro Performance.: The study provides a comparative analysis of spray-congealing and wet-sieving processes in engineering carrier particles for inhalation, utilizing a-Lactose monohydrate (Pinto et al., 2021).

  • Conversion of a-lactose monohydrate to anhydrous form with superior tabletability by twin-screw extrusion at elevated temperature.: Discusses a method for converting a-Lactose monohydrate to a more compressible anhydrous form, enhancing its application in tablet manufacturing (Batra et al., 2020).

生化/生理作用

α-乳糖是牛奶中主要的糖,也是新生哺乳动物通过母′乳喂养获得的主要能量来源。它能被肠道乳糖酶(EC 3.2.1.108)消化,肠道乳糖酶是一种在新生儿中表达的酶。断奶后,这种酶′的活性下降,导致成年哺乳动物出现乳糖不耐受。

其他說明

为了全面了解我们针对客户研究提供的各种双糖产品,建议您访问我们的碳水化合物分类页面。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Johannes Gursch et al.
Journal of pharmaceutical sciences, 104(10), 3481-3489 (2015-07-07)
Over the last years, continuous manufacturing has created significant interest in the pharmaceutical industry. Continuous filtration at low flow rates and high solid loadings poses, however, a significant challenge. A commercially available, continuously operating, dynamic cross-flow filtration device (CFF) is
Sha Liu et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 96, 132-142 (2015-07-30)
Co-administration of an inhaled corticosteroid and long acting beta agonist for chronic obstructive pulmonary disease has reduced mortality compared to either drug alone. This combination reduces exacerbations, hospitalization, emergency department visits and health care costs. A novel fixed-dose combination of

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