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Merck

L3625

Sigma-Aldrich

α-乳糖 一水合物

≥99% total lactose basis (GC)

别名:

β-D-Gal-(1→4)-α-D-Glc, 4-O-β- D -半乳糖基-α- D -葡萄糖, 乳糖

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About This Item

经验公式(希尔记法):
C12H22O11 · H2O
CAS号:
分子量:
360.31
MDL號碼:
分類程式碼代碼:
12352201
PubChem物質ID:
NACRES:
NA.25

生物源

bovine milk

化驗

≥99% total lactose basis (GC)

形狀

powder

雜質

≤0.05% Glucose
≤4% β-lactose

顏色

white to off-white

mp

219  °C ((426 °F ))

溶解度

water: 100 mg/mL, clear, colorless

儲存溫度

room temp

SMILES 字串

[H]O[H].OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C12H22O11.H2O/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17;/h3-20H,1-2H2;1H2/t3-,4-,5+,6+,7-,8-,9-,10-,11+,12+;/m1./s1

InChI 密鑰

WSVLPVUVIUVCRA-KPKNDVKVSA-N

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應用


  • Crystal size, a key character of lactose crystallization affecting microstructure, surface chemistry and reconstitution of milk powder.: This study uses alpha-lactose monohydrate as a standard to investigate how crystal size affects the physical properties of milk powder, which is crucial for optimizing production processes in the dairy industry (Qi X et al., 2024).

  • Predicting the Strength of Cohesive and Adhesive Interparticle Interactions for Dry Powder Inhalation Blends of Terbutaline Sulfate with alpha-Lactose Monohydrate.: Explores the critical role of alpha-lactose monohydrate, as an excipient together with terbutaline sulfate in optimizing particle interactions for enhanced performance of inhalable therapeutics (Ma CY et al., 2023).

  • Terahertz time-domain spectroscopy for the investigation of tablets prepared from roller compacted granules.: This research utilizes alpha-lactose monohydrate to examine the properties of pharmaceutical tablets, offering insights into material characteristics that affect drug delivery systems (Anuschek M et al., 2023).

生化/生理作用

α-乳糖是牛奶中主要的糖,也是新生哺乳动物通过母乳喂养获得的主要能量来源。它能被肠道乳糖酶(EC 3.2.1.108)消化,肠道乳糖酶是一种在新生儿中表达的酶。断奶后,这种酶的活性下降,导致成年哺乳动物出现乳糖不耐受。
乳糖是由一个半乳糖和一个葡萄糖分子经过缩合反应形成的二糖。乳糖是大多数物种乳汁中主要的糖,含量通常为2-8%。

其他說明

为了全面了解我们针对客户研究提供的各种双糖产品,建议您访问我们的碳水化合物分类页面。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Gwenola Le Dréan et al.
Nutrients, 11(9) (2019-08-24)
Oligosaccharides (OS) are commonly added to infant formulas, however, their physiological impact, particularly on adult health programming, is poorly described. In adult animals, OS modify microbiota and stimulate colonic fermentation and enteroendocrine cell (EEC) activity. Since neonatal changes in microbiota
Helena Montanuy et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 26(12), 3044-3057 (2020-02-02)
Fanconi anemia rare disease is characterized by bone marrow failure and a high predisposition to solid tumors, especially head and neck squamous cell carcinoma (HNSCC). Patients with Fanconi anemia with HNSCC are not eligible for conventional therapies due to high
Johannes Gursch et al.
Journal of pharmaceutical sciences, 104(10), 3481-3489 (2015-07-07)
Over the last years, continuous manufacturing has created significant interest in the pharmaceutical industry. Continuous filtration at low flow rates and high solid loadings poses, however, a significant challenge. A commercially available, continuously operating, dynamic cross-flow filtration device (CFF) is
Sha Liu et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 96, 132-142 (2015-07-30)
Co-administration of an inhaled corticosteroid and long acting beta agonist for chronic obstructive pulmonary disease has reduced mortality compared to either drug alone. This combination reduces exacerbations, hospitalization, emergency department visits and health care costs. A novel fixed-dose combination of

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