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Merck

I3661

Sigma-Aldrich

Insulin-FITC labeled human

recombinant, expressed in yeast, lyophilized powder

别名:

FITC Insulin, Labeled Human Insulin

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About This Item

EC號碼:
分類程式碼代碼:
12352204
NACRES:
NA.83

重組細胞

expressed in yeast

品質等級

形狀

lyophilized powder
solid

成份

Insulin, ≥75% biuret

標籤範圍

≥1 mol FITC per mol insulin

運輸包裝

dry ice
dry ice

儲存溫度

−20°C
−20°C

一般說明

Insulin is a polypeptide hormone mainly secreted from pancreas when glucose level changes in the plasma. It is an anabolic hormone and enhances the generation of storage substances, for instance glycogen, fat and protein. It also induces glucose uptake by peripheral tissues, thereby controlling glucose levels in the plasma. Its main sites of action are liver, adipose tissue and muscle.

應用

Insulin-FITC labeled human has been used in primary endothelial cells from human adipose tissue microvasculature (HAMEC) to study insulin transcytosis.

外觀

含有磷酸钠缓冲盐的冻干粉

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Espinal J
Understanding Insulin Action: Principles and Molecular Mechanisms (1989)
Cristina C Clement et al.
Scientific reports, 8(1), 11253-11253 (2018-07-28)
Transport of tissue-derived lymphatic fluid and clearance by draining lymph nodes are pivotal for maintenance of fluid homeostasis in the body and for immune-surveillance of the self- and non-self-proteomes. Yet a quantitative analysis of nodal filtration of the tissue-derived proteome
Mahmoud S Alghamri et al.
ACS nano, 16(6), 8729-8750 (2022-05-27)
Glioblastoma (GBM) is an aggressive primary brain cancer, with a 5 year survival of ∼5%. Challenges that hamper GBM therapeutic efficacy include (i) tumor heterogeneity, (ii) treatment resistance, (iii) immunosuppressive tumor microenvironment (TME), and (iv) the blood-brain barrier (BBB). The
Aaron L Glieberman et al.
Lab on a chip, 19(18), 2993-3010 (2019-08-30)
Pancreatic β cell function is compromised in diabetes and is typically assessed by measuring insulin secretion during glucose stimulation. Traditionally, measurement of glucose-stimulated insulin secretion involves manual liquid handling, heterogeneous stimulus delivery, and enzyme-linked immunosorbent assays that require large numbers
Hanwoong Woo et al.
Molecular brain, 11(1), 37-37 (2018-07-05)
Chronic stress is a psychologically significant factor that impairs learning and memory in the hippocampus. Insulin signaling is important for the development and cognitive function of the hippocampus. However, the relation between chronic stress and insulin signaling at the molecular

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