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Merck

H7379

Sigma-Aldrich

血红蛋白 人

lyophilized powder

别名:

HB

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About This Item

CAS号:
MDL號碼:
分類程式碼代碼:
12352202
eCl@ss:
42030116
NACRES:
NA.61

生物源

human

形狀

lyophilized powder

技術

enzyme immunoassay: suitable

雜質

HIV and hepatitis B antigen, tested negative

溶解度

H2O: soluble 20 mg/mL

儲存溫度

2-8°C

一般說明

血红蛋白是红细胞的主要成分,也是红细胞呈现红色的原因。它在红细胞中的正常浓度为34%。由于它能够将氧从肺部输送到身体组织,促进二氧化碳的返回转运,因此血红蛋白是脊椎动物最重要的呼吸蛋白。

應用

血红蛋白被用于开发检测视黄醇结合蛋白的快速酶免疫分析法。它也被内皮源性舒张因子用于抑制人血小板反应性。

生化/生理作用

Fe2+/Fe3+平衡是血液氧合的生理指标。脱氧血红蛋白通过将亚硝酸盐还原为NO(一种血管舒张剂,可促进血液流向缺氧组织)来辅助反馈回路。
氧气转运蛋白,NO清除剂

注意

由于天然血红蛋白在空气中容易氧化,因此这些制剂可能主要是高铁血红蛋白。

免責聲明

仅供研究使用。本品在法国的科研应用受到监管,包括用于进口和出口活动(法国《公共卫生法典》Public Health Code Article L 1211-1 paragraph 2)。如《公共卫生法典》所述,购买者(即最终用户)需要从法国研究部(France Ministry of Research)获得进口授权。订购此产品即代表您已确认获得合法的进口授权。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Chiao-Wang Sun et al.
Circulation, 139(23), 2654-2663 (2019-03-25)
Nitrosation of a conserved cysteine residue at position 93 in the hemoglobin β chain (β93C) to form S-nitroso (SNO) hemoglobin (Hb) is claimed to be essential for export of nitric oxide (NO) bioactivity by the red blood cell (RBC) to
Leila Pishkar et al.
Journal of biomolecular structure & dynamics, 35(3), 603-615 (2016-05-07)
In this study, a novel method to probe molecular interactions and binding of human hemoglobin (Hb) with nanodiamond (ND) was introduced based on the surface tension measurement. This method complements conventional techniques, which are basically done by zeta potential and
Mieke Steenbeke et al.
Clinical chemistry and laboratory medicine, 58(10), 1759-1767 (2020-07-11)
Objectives In this study, the possibilities of Fourier-transformed infrared spectroscopy (FTIR) for analysis of urine sediments and for detection of bacteria causing urinary tract infections (UTIs) were investigated. Methods Dried urine specimens of control subjects and patients presenting with various
Nai-Jia Huang et al.
Nature communications, 8(1), 423-423 (2017-09-06)
A short half-life in the circulation limits the application of therapeutics such as single-domain antibodies (VHHs). We utilize red blood cells to prolong the circulatory half-life of VHHs. Here we present VHHs against botulinum neurotoxin A (BoNT/A) on the surface
Rebeca M Torrente-Rodríguez et al.
PloS one, 12(4), e0175056-e0175056 (2017-04-05)
The first electrochemical immunosensor for the determination of fibroblast growth factor receptor 4 (FGFR4) biomarker is reported in this work. The biosensor involves a sandwich configuration with covalent immobilization of a specific capture antibody onto activated carboxylic-modified magnetic microcarriers (HOOC-MBs)

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