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Merck

H0377

Sigma-Aldrich

5-羟基-DL-赖氨酸 盐酸盐

≥98% (TLC)

别名:

2,6-Diamino-5-hydroxycaproic acid 盐酸盐, 2,6-二氨基-5-羟基己酸 盐酸盐

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About This Item

线性分子式:
NH2CH2CH(OH)CH2CH2CH(NH2)COOH · HCl
CAS号:
分子量:
198.65
Beilstein:
3914368
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.26

product name

5-羟基-DL-赖氨酸 盐酸盐,

化驗

≥98% (TLC)

形狀

powder

顏色

white

mp

225 °C (dec.) (lit.)

應用

detection
peptide synthesis

SMILES 字串

Cl.NCC(O)CCC(N)C(O)=O

InChI

1S/C6H14N2O3.ClH/c7-3-4(9)1-2-5(8)6(10)11;/h4-5,9H,1-3,7-8H2,(H,10,11);1H

InChI 密鑰

MJXVOTKVFFAZQJ-UHFFFAOYSA-N

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應用


  • Characterization of acetyl-CoA: L-lysine N6-acetyltransferase, which catalyses the first step of carbon catabolism from lysine in Saccharomyces cerevisiae.: This research investigates the enzyme acetyl-CoA: L-lysine N6-acetyltransferase, which initiates the catabolism of lysine in Saccharomyces cerevisiae. Utilizing DL-5-Hydroxylysine hydrochloride, the study provides insights into the metabolic pathways and regulatory mechanisms of lysine degradation, contributing to the broader understanding of amino acid metabolism in yeast (Bode et al., 1993).

生化/生理作用

DL-5-羟基赖氨酸是5-羟基赖氨酸的D-和L-对映异构体的外消旋混合物,可用作自由基诱导的蛋白质氧化的潜在靶标。

其他說明

混合DL和DL-allo

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析证书(COA)

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E R Stadtman et al.
Amino acids, 25(3-4), 207-218 (2003-12-09)
We summarize here results of studies designed to elucidate basic mechanisms of reactive oxygen (ROS)-mediated oxidation of proteins and free amino acids. These studies have shown that oxidation of proteins can lead to hydroxylation of aromatic groups and aliphatic amino
R Bode et al.
Archives of microbiology, 160(5), 397-400 (1993-01-01)
The carbon catabolism of L-lysine starts in Saccharomyces cerevisiae with acetylation by an acetyl-CoA:L-lysine N6-acetyltransferase. The enzyme is strongly induced in cells grown on L-lysine as sole carbon source and has been purified about 530-fold. Its activity was specific for
B Morin et al.
Chemical research in toxicology, 11(11), 1265-1273 (1998-11-17)
gamma-Irradiation of several amino acids (Val, Leu, Ile, Lys, Pro, and Glu) in the presence of O2 generates hydroperoxides. We have previously isolated and characterized valine and leucine hydroperoxides, and hydroxides, and have detected these products in both isolated systems
Giuseppe Forlani et al.
Frontiers in plant science, 11, 582026-582026 (2020-11-17)
Because proline accumulates rapidly in response to several stress conditions such as drought and excess salt, increased intracellular levels of free proline are considered a hallmark of adaptive reactions in plants, particularly in response to water stress. Proline quantitation is
Rafal Mól et al.
Plant & cell physiology, 45(10), 1396-1405 (2004-11-27)
The role of ethylene and auxin in stigma-to-ovule signalling was investigated in maize (Zea mays L.). Maturation of the egg cells in an ear was stimulated before actual fertilization by the application of fresh pollen grains or quartz sand to

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