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COO原产地证书/COA分析证书

EHU108601

MISSION^® esiRNA

Name: MISSION<SUP>®</SUP> esiRNA
Brand: SIGMA

targeting human RBM4, RBM14-RBM4

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About This Item

分類程式碼代碼:

41105324

NACRES:

NA.51

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Sigma-Aldrich

MSQC24

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MSQC26

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MSQC22

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MSQC4

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Sigma-Aldrich

C8667

胆固醇

Sigma-Aldrich

EMU004461

MISSION^® esiRNA

Supelco

PHR1533

胆固醇

HS120052

DuraPorter^® specimen transport box

描述

品質等級

100

產品線

MISSION^®

形狀

lyophilized powder

esiRNA cDNA 標靶序列

GGAGATTCGCTCACTCTTCGAGCAGTATGGGAAGGTGCTGGAATGTGACATCATTAAGAATTACGGCTTTGTGCACATAGAAGACAAGACGGCAGCTGAGGATGCCATACGCAACCTGCACCATTACAAGCTTCATGGGGTGAACATCAACGTGGAAGCCAGCAAGAATAAGAGCAAAACCTCAACAAAGTTGCATGTGGGCAACATCAGTCCCACCTGCACCAATAAGGAGCTTCGAGCCAAGTTTGAGGAGTATGGTCCGGTCATCGAATGTGACATCGTGAAAGATTATGCCTTCGTACACATGGAGCGGGCAGAGGATGCAGTGGAGGCCATCAGGGGCCTTGATAACACAGAGTTTCAAGGCAAACGAATGCACGTGCAGTTGTCCACCAGCCGGCTTAGGACTGCGCCCGGGATGGGAGACCAGAGCGGCTGCTATCGGTGCGGGAAAGAGGGGCACTGGTCCAAAGAGTGTCCG

Ensembl | 人類登錄號

ENSG00000173933

NCBI登錄號

NM_002896.3

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

human ... RBM4(100526737) , RBM4(5936)

一般說明

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析证书(COA)

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Natural antisense transcript TPM1-AS regulates the alternative splicing of tropomyosin I through an interaction with RNA-binding motif protein 4.

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The international journal of biochemistry & cell biology, 90, 59-67 (2017-07-30)

LncRNAs play a vital role in alternative splicing of target genes. However, the mechanisms underlying lncRNAs involvement in splicing are poorly understood. In the present study, we identified a previously uncharacterized lncRNA, which is denoted as TPM1-AS, is reverse-transcribed from

Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities.

S Kagawa et al.

Oncogene, 34(18), 2347-2359 (2014-06-17)

Notch activity regulates tumor biology in a context-dependent and complex manner. Notch may act as an oncogene or a tumor-suppressor gene even within the same tumor type. Recently, Notch signaling has been implicated in cellular senescence. Yet, it remains unclear

Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles.

Sven Hennig et al.

The Journal of cell biology, 210(4), 529-539 (2015-08-19)

Prion-like domains (PLDs) are low complexity sequences found in RNA binding proteins associated with the neurodegenerative disorder amyotrophic lateral sclerosis. Recently, PLDs have been implicated in mediating gene regulation via liquid-phase transitions that drive ribonucleoprotein granule assembly. In this paper

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MISSION^® esiRNA