所有图片(4)
About This Item
经验公式（希尔记法）:
C19H30O4
CAS号:
分子量:
322.44
MDL编号:
UNSPSC代码:
12162212
PubChem化学物质编号:
NACRES:
NA.25
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方案
≥97% (HPLC)
表单
liquid
储存温度
−20°C
SMILES字符串
CCCCCCCCCCC1=C(C)C(=O)C(OC)=C(OC)C1=O
InChI
1S/C19H30O4/c1-5-6-7-8-9-10-11-12-13-15-14(2)16(20)18(22-3)19(23-4)17(15)21/h5-13H2,1-4H3
InChI key
VMEGFMNVSYVVOM-UHFFFAOYSA-N
一般描述
泛醌类似物。
线粒体通透性转换孔 (MPTP) 抑制剂。
应用
- 作为钯诱导脂肪毒性中介物的溶酶体钙（2+）。: 该研究探索了癸基泛醌（decylubiquinone）在调节溶酶体钙（2+）水平中的作用，提供了有关脂肪毒性机制和代谢疾病潜在治疗应用的见解（Oh et al., 2023）。
- VI型硫化物中的醌结合位点:醌氧化还原酶。：该论文研究了癸基泛醌在硫化物:醌氧化还原酶中的结合动力学,阐明了其在微生物呼吸中的作用和潜在生物技术应用（Miklovics et al., 2022）。
- 癸基泛醌对B16F10诱导小鼠中继发性黑色素瘤的保护作用。: 该研究展示了癸基泛醌在黑色素瘤小鼠模型中的抗转移性质，重点介绍了其成为癌症治疗中治疗药的潜力（Chatterjee et al., 2023）。
- 癸基泛醌通过上调Sirtuin2来抑制结肠直肠癌细胞生长。: 该研究确认了癸基泛醌是通过调节Sirtuin2表达，而成为结肠直肠癌细胞生长的抑制剂，研究暗示了其在癌症治疗中的应用（Li et al., 2021）。
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
其他客户在看
Samuel S W Szeto et al.
The Journal of biological chemistry, 287(27), 22509-22520 (2012-05-11)
Succinate dehydrogenase (SDH), also known as complex II, is required for respiratory growth; it couples the oxidation of succinate to the reduction of ubiquinone. The enzyme is composed of two domains. A membrane-extrinsic catalytic domain composed of the Sdh1p and
Zeqi Zheng et al.
International journal of nanomedicine, 15, 4501-4521 (2020-07-02)
Elevation of blood homocysteine (Hcy) level (hyperhomocysteinemia) is a risk factor for cardiovascular disorders and is closely associated with endothelial dysfunction. The present study aims to investigate the protective effect and underlying mechanism of nanoscale selenium (Nano-Se) in Hcy-mediated vascular
Hannah R Bridges et al.
Nature communications, 11(1), 5261-5261 (2020-10-18)
Respiratory complex I (NADH:ubiquinone oxidoreductase) captures the free energy from oxidising NADH and reducing ubiquinone to drive protons across the mitochondrial inner membrane and power oxidative phosphorylation. Recent cryo-EM analyses have produced near-complete models of the mammalian complex, but leave
Matthias L Jauslin et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 17(13), 1972-1974 (2003-08-19)
Friedreich Ataxia (FRDA), the most common inherited ataxia, arises from defective expression of the mitochondrial protein frataxin, which leads to increased mitochondrial oxidative damage. Therefore, antioxidants targeted to mitochondria should be particularly effective at slowing disease progression. To test this
Klaudia Borysiuk et al.
Frontiers in plant science, 9, 667-667 (2018-06-09)
Nitrate (NO3-) and ammonium (NH4+) are prevalent nitrogen (N) sources for plants. Although NH4+ should be the preferred form of N from the energetic point of view, ammonium nutrition often exhibits adverse effects on plant physiological functions and induces an
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