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Merck

D1068

Sigma-Aldrich

DCB

≥98% (HPLC), solid

别名:

3,3′-二氯苯甲嗪, NSC 67224

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About This Item

经验公式(希尔记法):
C14H10Cl2N2
CAS号:
分子量:
277.15
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

化驗

≥98% (HPLC)

形狀

solid

儲存條件

desiccated
under inert gas

顏色

yellow

溶解度

DMSO: ~6.8 mg/mL
H2O: insoluble

儲存溫度

2-8°C

SMILES 字串

Clc1cccc(\C=N\N=C\c2cccc(Cl)c2)c1

InChI

1S/C14H10Cl2N2/c15-13-5-1-3-11(7-13)9-17-18-10-12-4-2-6-14(16)8-12/h1-10H/b17-9+,18-10+

InChI 密鑰

XMOVWXSCYLINBJ-BEQMOXJMSA-N

生化/生理作用

3,3′-二氯苯甲醛嗪(DCB)可用作具有中性协同作用的变构配体。在3,3′-二氟苯甲醛嗪(DFB)的帮助下,它可以阻断mGluRs(代谢型谷氨酸受体亚型5(mGluR5))的正向别构调节作用,以及3,3′-二甲氧基苯甲醛嗪(DMeOB)的负调节作用。
代谢型谷氨酸受体mGluR5的中性别构调节剂。

特點和優勢

该化合物是《受体分类及信号转导》手册上谷氨酸受体(G蛋白家族)页面上的特色化合物。想要浏览手册的其他页面, 请单击此处

訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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