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方案
≥98% (HPLC)
表单
solid
储存条件
desiccated
溶解性
DMSO: 24 mg/mL
储存温度
2-8°C
SMILES字符串
Oc1ccc(Cl)cc1N2C(SCC2=O)c3cccc(Br)c3
InChI
1S/C15H11BrClNO2S/c16-10-3-1-2-9(6-10)15-18(14(20)8-21-15)12-7-11(17)4-5-13(12)19/h1-7,15,19H,8H2
InChI key
KEGQNJITMFBVAC-UHFFFAOYSA-N
生化/生理作用
CK-548 inhibits the activity of actin-related protein (Arp)2/3 complex by inserting into the hydrophobic core of Arp3 and altering its conformation.
CK-548 inhibits the activity of actin-related protein (Arp)2/3 complex by inserting into the hydrophobic core of Arp3 and altering its conformation: inhibits
警示用语:
Warning
危险声明
预防措施声明
危险分类
Acute Tox. 4 Oral - Aquatic Acute 1
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Renu Khasa et al.
Microbial pathogenesis, 149, 104565-104565 (2020-10-16)
Multiple membrane trafficking networks operate in the eukaryotic cell and are hijacked by viruses to establish infection. Recent studied have highlighted that viruses can exploit distinct pathways depending on the cell type. Japanese encephalitis virus (JEV), a neurotropic flavivirus, can
Arnat Balabiyev et al.
Molecular biology of the cell, 31(18), 2002-2020 (2020-06-25)
Macrophage fusion resulting in the formation of multinucleated giant cells (MGCs) is a multistage process that requires many adhesion-dependent steps and involves the rearrangement of the actin cytoskeleton. The diversity of actin-based structures and their role in macrophage fusion is
Renu Khasa et al.
The Journal of general virology, 100(2), 176-186 (2018-11-30)
Japanese encephalitis virus (JEV), a mosquito-borne flavivirus, is one of the leading global causes of virus-induced encephalitis. The infectious life-cycle of viruses is heavily dependent on the host membrane trafficking network. Here, we have performed a RNA-interference-based screen using a
Monika Hartmann et al.
Molecular cancer research : MCR, 13(5), 879-890 (2015-02-06)
Ectodomain cleavage (shedding) of transmembrane proteins by metalloproteases (MMP) generates numerous essential signaling molecules, but its regulation is not totally understood. CD44, a cleaved transmembrane glycoprotein, exerts both antiproliferative or tumor-promoting functions, but whether proteolysis is required for this is
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