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About This Item
经验公式（希尔记法）:
C30H37NO6
CAS号:
分子量:
507.62
Beilstein:
1632828
MDL號碼:
分類程式碼代碼:
51102829
PubChem物質ID:
NACRES:
NA.85
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生物源
Zygosporium mansonii
品質等級
形狀
solution
濃度
5 mg/mL in DMSO
抗生素活性譜
fungi
作用方式
enzyme | interferes
運輸包裝
wet ice
儲存溫度
−20°C
SMILES 字串
[H][C@@]12[C@H](C)C(=C)[C@@H](O)[C@@H]3\C=C\C[C@H](C)C(=O)[C@](C)(O)\C=C\[C@@H](OC(C)=O)[C@@]13C(=O)N[C@H]2Cc4ccccc4
InChI
1S/C30H37NO6/c1-17-10-9-13-22-26(33)19(3)18(2)25-23(16-21-11-7-6-8-12-21)31-28(35)30(22,25)24(37-20(4)32)14-15-29(5,36)27(17)34/h6-9,11-15,17-18,22-26,33,36H,3,10,16H2,1-2,4-5H3,(H,31,35)/b13-9+,15-14+/t17-,18+,22-,23-,24+,25-,26+,29+,30+/m0/s1
InChI 密鑰
SDZRWUKZFQQKKV-JHADDHBZSA-N
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應用
细胞松弛素D是黑僵菌代谢物的同分异构体。细胞松弛素D具有抗菌和抗肿瘤活性。它还会有害于肌动蛋白丝的长时程增强作用(LTP)的维持。它与促进有利于肌动蛋白解聚的条件有关。
生化／生理作用
细胞渗透性真菌毒素；肌动蛋白聚合的有效抑制剂。破坏肌动蛋白微丝并激活p53依赖性通路，引起细胞周期在G1-S过渡期阻滞。抑制平滑肌收缩。抑制胰岛素刺激而非基础的葡萄糖转运。
肌动蛋白聚合的强效抑制剂；可破坏肌动蛋白微丝；激活p53依赖性通路；抑制平滑肌收缩；抑制胰岛素刺激的葡萄糖转运。
其他說明
保持容器密闭，并置于干燥通风处。打开后的容器必须小心重新密封并保持直立以防止泄漏。
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 2
閃點（°F）
188.6 °F - closed cup - Solvent
閃點（°C）
87 °C - closed cup - Solvent
個人防護裝備
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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