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应用
Blue Carrier是一种从软体动物智利鲍鱼的血淋巴中分离得到的载氧蛋白。它具有高度的免疫原性，可用作产生小分子抗体的载体蛋白。该方案的一个例子是关于肌胃糜烂素抗体的生产。
血蓝蛋白是用于抗体生产的载体蛋白。在膀胱癌的治疗中，它用于促进半抗原和肽抗体的生产，是癌症疫苗的一中成分。
生化/生理作用
用于抗体生产的高可溶性载体蛋白
外形
100 mg溶于0.5 mL 0.15 M NaCl、0.1 M磷酸钠，pH 7.2
法律信息
Blue Carrier is a registered trademark of Biosonda S.A.
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Harold Oliva et al.
Hybridoma and hybridomics, 21(5), 365-374 (2002-12-10)
We studied the reactivity of mouse monoclonal antibodies (MAbs) against the hemocyanin from the Chilean marine gastropod Concholepas concholepas (CCH). This protein has been successfully used as a carrier to produce antibodies to haptens and peptides. All MAbs (13) belonging
M I Becker et al.
Hybridoma, 17(4), 373-381 (1998-10-28)
This study is the first report of the development of monoclonal antibodies (MAbs) against gizzerosine (GZ), one of the causative agents of black vomit, a serious poultry disease. Balb/c mice were immunized with different GZ conjugates; the most immunogenic conjugate
Enhanced structural stability of Concholepas hemocyanin increases its immunogenicity and maintains its non-specific immunostimulatory effects.
Arancibia S., et al.
European Journal of Immunology (2011)
Bruno Moltedo et al.
The Journal of urology, 176(6 Pt 1), 2690-2695 (2006-11-07)
We determined the antitumor properties of a newly available hemocyanin obtained from the Chilean gastropod Concholepas concholepas (Biosonda Corp., Santiago, Chile) in a syngeneic heterotopic mouse bladder carcinoma model. Since keyhole limpet hemocyanin (Pierce, Rockford, Illinois) is used increasingly in
Anaphylaxis caused by hemocyanin contained in shrimp cephalothorax.
Daiana Guillen et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 113(6), 674-675 (2014-10-14)
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