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一般描述
心磷脂位于线粒体内膜，含有18个碳原子，由“甘油桥”连接的3-磷脂酰基团组成。心磷脂是ATP合成酶的重要组分。
应用
心磷脂钠盐（来源于牛心脏）已用于：
- 作为薄层色谱法定量分析粗糙脉孢菌总线粒体脂质的磷脂标准品(89)
- 作为反相高效液相色谱(RP-HPLC)定量分析细菌脂质提取物的内部标准品(90)
- 作为抗原用于评估系统性红斑狼疮(SLE)患者的IgM反应(91)
生化/生理作用
心磷脂是一种在哺乳动物组织中发现的浓度很低的线粒体磷脂。它通常是膜的成分。抑制纤连蛋白、玻连蛋白和 I 型胶原蛋白对细胞的附着。
包装
在氩气下包装
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Ze-Wei Ma et al.
Acta pharmacologica Sinica, 39(6), 1012-1021 (2017-12-22)
Humanin (HN) is a 24-residue peptide identified from the brain of a patient with Alzheimer's disease (AD). HN has been found to protect against neuronal insult caused by Aβ peptides or transfection of familial AD mutant genes. In order to
Analysis of mutations in Neurospora crassa ERMES components reveals specific functions related to beta-barrel protein assembly and maintenance of mitochondrial morphology
Wideman JG, et al.
PLoS ONE, 8(8), e71837-e71837 (2013)
Lu Luo et al.
The Journal of biological chemistry, 289(46), 31708-31718 (2014-10-08)
Bax is a pro-apoptotic Bcl-2 family protein. The activated Bax translocates to mitochondria, where it forms pore and permeabilizes the mitochondrial outer membrane. This process requires the BH3-only activator protein (i.e. tBid) and can be inhibited by anti-apoptotic Bcl-2 family
Effects of pure n-alkanes and crude oil on bacterial phospholipid classes and molecular species determined by electrospray ionization mass spectrometry
Mazzella N, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 822(1-2), 40-53 (2005)
Epstein-Barr virus antibodies mark systemic lupus erythematosus and scleroderma patients negative for anti-DNA
Fattal I, et al.
Immunology, 141(2), 276-285 (2014)
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