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产品名称
4-(3-丁氧基-4-甲氧基苄基)咪唑烷-2-酮, solid
生物源
synthetic (organic)
品質等級
化驗
≥98% (HPLC)
形狀
solid
溶解度
ethanol: 7 mg/mL
H2O: insoluble
儲存溫度
room temp
SMILES 字串
CCCCOc1cc(CC2CNC(=O)N2)ccc1OC
InChI
1S/C15H22N2O3/c1-3-4-7-20-14-9-11(5-6-13(14)19-2)8-12-10-16-15(18)17-12/h5-6,9,12H,3-4,7-8,10H2,1-2H3,(H2,16,17,18)
InChI 密鑰
PDMUULPVBYQBBK-UHFFFAOYSA-N
基因資訊
human ... LITAF(9516) , PDE4B(5142) , PRKAR1A(5573) , PRKAR1AP(5574) , PRKAR1B(5575) , PRKAR2A(5576) , PRKAR2B(5577)
rat ... Pde4a(25638)
應用
4-(3-丁氧基-4-甲氧基苄基)咪唑烷-2-酮已用于:
- 作为环腺苷单磷酸(cAMP)磷酸二酯酶抑制剂来处理细胞,用于测定细胞内cAMP水平
- 作为无血清培养基成分
- 作为磷酸二酯酶抑制剂,研究蛋白酶激活受体-1 (PAR-1)激活对cAMP水平的影响
生化/生理作用
cAMP 磷酸二酯酶的抑制剂。在主动脉的血管平滑肌中的 IC50 值为 33 μM 。
特點和優勢
这种化合物是环核苷酸研究的特色产品。点击此处发现更多特色环核苷酸产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
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