跳转至内容
Merck
所有图片(1)

主要文件

查看所有文档

B6936

Sigma-Aldrich

3-联苯氨基-6-(4-氯苯基)哒嗪

≥98% (HPLC), solid

别名:

BCP

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C22H17N4Cl
CAS号:
901773-91-9
分子量:
372.85
MDL编号:
MFCD11046030
UNSPSC代码:
12352202
PubChem化学物质编号:
329773289
NACRES:
NA.77

方案

≥98% (HPLC)

表单

solid

颜色

light yellow

溶解性

DMSO: >14 mg/mL

储存温度

2-8°C

SMILES字符串

Nc1ccc(cc1)-c2ccc(Nc3ccc(nn3)-c4ccc(Cl)cc4)cc2

InChI

1S/C22H17ClN4/c23-18-7-1-17(2-8-18)21-13-14-22(27-26-21)25-20-11-5-16(6-12-20)15-3-9-19(24)10-4-15/h1-14H,24H2,(H,25,27)

InChI key

ABGCSSPCKSVMHI-UHFFFAOYSA-N

生化/生理作用

3-Benzidino-6-(4-chlorophenyl)pyridazine is an inhibitor of delayed rectifier and transient outward potassium currents.
3-Benzidino-6-(4-chlorophenyl)pyridazine is an inhibitor of delayed rectifier and transient outward potassium currents. The IC50 values for the blocking action of BCP on IKDR and IKA was calculated as 7.13 μM and 0.55 μM, respectively in acutely isolated rat hippocampal pyramidal neurons by using whole-cell patch-clamp technique. The parent compound, minaprine (Cat. No. M3157), has selective affinity for M1 muscarinic receptors and possesses memory-enhancing properties and also acts as an antidepressant.

特点和优势

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

象形图

Skull and crossbones
GHS06

警示用语：

Danger

危险声明

H301

危险分类

Acute Tox. 3 Oral

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
087K4602

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Richard K Sterling et al.
The American journal of gastroenterology, 114(5), 746-757 (2018-11-10)
Because most HBV/HIV co-infected patients on combination antiretroviral therapy (cART) have suppressed HBV DNA and normal liver enzymes, the histologic spectrum of liver disease in HBV/HIV coinfection is poorly defined. To address this gap in knowledge, we conducted a prospective
Anne-Els van de Logt et al.
Kidney international, 95(6), 1514-1517 (2019-05-06)
Differences between laboratory assays can have important clinical implications. For creatinine assays this became apparent soon after the introduction of the Modification of Diet in Renal Disease formula and resulted in international efforts towards standardization. Albumin in blood is measured
Joseph D Hill et al.
Scientific reports, 7(1), 5250-5250 (2017-07-14)
Bulk fabrication of surface patterns with sub-20 nm feature sizes is immensely desirable for many existing and emerging technologies. Directed self-assembly (DSA) of block copolymers (BCPs) has been a recently demonstrated approach to achieve such feature resolution over large-scale areas with
Qian Tang et al.
Theranostics, 9(4), 1125-1143 (2019-03-15)
Incorporating a biomimetic coating and integrating osteoinductive biomolecules into basic bone substitutes are two common strategies to improve osteogenic capabilities in bone tissue engineering. Currently, the underlying mechanism of osteoporosis (OP)-related deficiency of osteogenesis remains unclear, and few treatments target
Moritz Flick et al.
European journal of pharmacology, 791, 718-725 (2016-10-30)
Caveolae, lipid enriched invaginations of the plasma membrane, are epicentres of cellular signal transduction. The structural proteins of caveolae, caveolins, regulate effector pathways in anaesthetic-induced cardioprotection, including the RISK pathway. Helium (He) postconditioning (HePoc) is known to mimic anaesthetic conditioning
查看所有相关文献

商品

钾通道

我们可提供多种与钙通道相关的产品以满足您的各类研究需求。

Potassium Channels

We offer many products related to potassium channels for your research needs.

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门