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Merck

A5486

Sigma-Aldrich

偶氮甲烷

13.4 M, ≥98%

别名:

AOM

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About This Item

线性分子式:
CH3N=N(→O)CH3
CAS号:
分子量:
74.08
MDL编号:
UNSPSC代码:
12352124
PubChem化学物质编号:
NACRES:
NA.25

方案

≥98%

表单

liquid

组成

methylene chloride, ≤1%

储存条件

(Keep container tightly closed in a dry and well-ventilated place.)

浓度

13.4 M

颜色

colorless

沸点

97-99 °C (lit.)

密度

0.991 g/mL at 25 °C (lit.)

应用

genomic analysis

储存温度

−20°C

SMILES字符串

C\N=[N+](/C)[O-]

InChI

1S/C2H6N2O/c1-3-4(2)5/h1-2H3/b4-3+

InChI key

DGAKHGXRMXWHBX-ONEGZZNKSA-N

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一般描述

偶氮甲烷(AOM)是一种功能强大的实验室化学品,用于研究癌症,特别是结肠癌的发生、进展和预防。它可用作引发肿瘤形成的致癌物和导致DNA特异性改变的基因突变剂。

应用

氧化偶氮甲烷(AOM),一种基因突变剂,可与硫酸葡聚糖钠(DSS)一起用于在实验室动物中创建癌症模型,从而用于研究癌症进展和化学预防的机制。

生化/生理作用

诱导DNA中O6-甲基鸟嘌呤加合物的致癌物导致G→A转变。 在实验动物的结肠中诱导肿瘤生成,并用于研究癌症进展和化学预防的机制。

特点和优势

用途广泛,适用于各种实验室和研究应用。

其他说明

为避免实验动物过早死亡,在实验设计中确定合适的氧化偶氮甲烷剂量至关重要。
如需了解生化试剂系列的更多信息,请填写此表

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警示用语:

Danger

危险分类

Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2

储存分类代码

3 - Flammable liquids

WGK

WGK 3

闪点(°F)

75.2 °F

闪点(°C)

24 °C


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