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應用
S-乙酰辅酶 A 合成酶可用于研究各种代谢途径，例如糖酵解、糖异生、丙酮酸代谢和 CO2 固定。它也可以用于基因表达研究。
来自面包酵母的 S-乙酰辅酶 A 合成酶已用于合成 5′-磷酸四磷酸腺苷和 5′-磷酸五磷酸腺苷。
生化／生理作用
乙酰辅酶 A 合成酶催化乙酰辅酶 A 的产生。它参与细胞核中的组蛋白乙酰化。它可能参与不可发酵碳源（如甘油）的生长。乙酰辅酶 A 合成酶是由乙酸盐、乙醛和乙醇诱导的。
包裝
包装尺寸基于蛋白质含量。
單位定義
在 37°C，pH 7.5 下，一个单位每分钟将从乙酸盐、ATP 和辅酶 A 生成 1.0 μ 摩尔 S-乙酰辅酶 A。
外觀
冻干粉末，含有稳定剂，如磷酸钾、蔗糖和还原型谷胱甘肽
訊號詞
Danger
危險聲明
危險分類
Resp. Sens. 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Saurabh Sahar et al.
The Journal of biological chemistry, 289(9), 6091-6097 (2014-01-16)
The circadian clock regulates a wide range of physiological and metabolic processes, and its disruption leads to metabolic disorders such as diabetes and obesity. Accumulating evidence reveals that the circadian clock regulates levels of metabolites that, in turn, may regulate
Sara Castaño-Cerezo et al.
Molecular microbiology, 82(5), 1110-1128 (2011-11-09)
Lysine acetylation is a well-established post-translational modification widely conserved and distributed in bacteria. Although multiple regulatory roles have been proved, little is known about its regulation. Here, we present evidence that the transcription of the Gcn5-like acetyltransferase YfiQ of Escherichia
Sergio Renilla et al.
Applied microbiology and biotechnology, 93(5), 2109-2124 (2011-09-02)
Impairment of acetate production in Escherichia coli is crucial for the performance of many biotechnological processes. Aerobic production of acetate (or acetate overflow) results from changes in the expression of central metabolism genes. Acetyl-CoA synthetase scavenges extracellular acetate in glucose-limited
Seunghoon Lee et al.
Eukaryotic cell, 10(8), 1043-1052 (2011-06-15)
Acetyl coenzyme A (acetyl-CoA) is a crucial metabolite for energy metabolism and biosynthetic pathways and is produced in various cellular compartments with spatial and temporal precision. Our previous study on ATP citrate lyase (ACL) in Gibberella zeae revealed that ACL-dependent
Adenosine 5'-tetraphosphate and adenosine 5'-pentaphosphate are synthesized by yeast acetyl coenzyme A synthetase.
Guranowski A, et al.
Journal of Bacteriology, 176(10), 2986-2990 (1994)
商品
Enzyme Reagent Coenzyme A (CoA, CoASH or HSCoA) is the key cofactor in first step of the TCA cycle, responsible for transferring the acetyl group from pyruvate oxidation to oxaloacetate yielding citrate. Available through Sigma-Aldrich online.
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