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Merck

93482

Sigma-Aldrich

苯甲磺酰氟 溶液

~0.1 M in ethanol (T)

别名:

PMSF, 苄磺酰氟

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About This Item

CAS号:
Beilstein:
2088311
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:
NACRES:
NA.77

生物源

microbial
synthetic

品質等級

形狀

liquid

濃度

~0.1 M in ethanol (T)

密度

0.797 g/mL at 20 °C

儲存溫度

2-8°C

SMILES 字串

FS(=O)(=O)Cc1ccccc1

InChI

1S/C7H7FO2S/c8-11(9,10)6-7-4-2-1-3-5-7/h1-5H,6H2

InChI 密鑰

YBYRMVIVWMBXKQ-UHFFFAOYSA-N

應用

苯甲基磺酰氟溶液被用作乳腺癌细胞系、纤维肉瘤细胞系和D5后脑和脊髓神经祖细胞的细胞裂解物缓冲液的组分。

生化/生理作用

施用PMSF可产生与其抗胆碱酯酶作用无关的镇痛作用,并延长中枢给药的β-内啡肽的镇痛作用。
苯甲基磺酰氟(PMSF)是丝氨酸蛋白酶抑制剂。它与蛋白酶的活性位点残基共价结合,抑制蛋白水解活性。PMSF可用在蛋白纯化过程中的细胞裂解物缓冲液中,防止靶蛋白降解。PMSF可有效抑制纳洛酮促发的戒断跳跃。

象形圖

FlameExclamation mark

訊號詞

Danger

危險聲明

危險分類

Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

53.6 °F - closed cup

閃點(°C)

12 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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