73156

N-Methyl-L-serine

≥98% (TLC)

• 别名: (S)-3-Hydroxy-2-(methylamino)propionic acid, N-Me-Ser-OH
• 经验公式（希尔记法）: C₄H₉NO₃
• CAS号: 2480-26-4
• 分子量: 119.12
• Beilstein: 2498641
• MDL编号: MFCD00037756
• UNSPSC代码: 12352202
• PubChem化学物质编号: 329764666
• NACRES: NA.32

属性

• 方案: ≥98% (TLC)
• 表单: powder
• 旋光性: [α]/D +9.5±1.0°, c = 1 in 1 M HCl
• 组成: carbon, 39.5-41.1% ; nitrogen, 11.5-12.0%
• 颜色: white
• mp: 204 °C
• SMILES字符串: CN[C@@H](CO)C(O)=O
• InChI: 1S/C4H9NO3/c1-5-3(2-6)4(7)8/h3,5-6H,2H2,1H3,(H,7,8)/t3-/m0/s1
• InChI key: PSFABYLDRXJYID-VKHMYHEASA-N

说明

生化/生理作用

N-Methyl amino acids play an important role in investigations on prevention or therapy of Alzheimer′s disease, neurofibrillary tangles or amyloid plaque are physiological characteristics of this disease and ?-amyloid(40) fibrillogenesis and disassembly of ?-amyloid(40) fibrils is inhibited by short ?-amyloid congeners containing N-methyl amino acids at alternate residue. N-Methyl-L-serine stimulates hyaluronan production in human skin fibroblasts.

N-Methyl-L-serine has been found to stimulate production of high molecular mass hyaluronan in human fibroblasts. This effect was specific to methylated L-serine and not observed with other methylated amino acids.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable