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化驗
≥95% (HPLC)
形狀
powder
顏色
yellow
mp
214-215 °C (lit.)
SMILES 字串
Oc1cc(O)c2C(=O)C(O)=C(Oc2c1)c3ccccc3
InChI
1S/C15H10O5/c16-9-6-10(17)12-11(7-9)20-15(14(19)13(12)18)8-4-2-1-3-5-8/h1-7,16-17,19H
InChI 密鑰
VCCRNZQBSJXYJD-UHFFFAOYSA-N
基因資訊
human ... ADORA2A(135) , ADORA3(140) , CYP1A2(1544)
rat ... Adora1(29290) , Adora2a(25369)
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一般說明
高良姜精是从姜科家族成员中分离出的一种类黄酮，主要用作草药。
應用
高良姜素已用于:
- 作为试验药物用于测试其在顺铂诱导的肾毒性啮齿动物模型中的改善作用
- 测试其对3T3-L1前脂肪细胞向脂肪细胞分化的影响
- 作为核磁共振波谱和质谱的内标物
生化／生理作用
高良姜精具有抗氧化、抗凋亡、抗炎和抗肥胖特性。此外，它还具有抵抗环境和饮食致癌物的抗遗传毒性。高良姜精通过阻止癌细胞增殖、诱导凋亡和自噬以及抑制转移来抑制癌细胞生长。高良姜精还具有抑制CYP1A1（细胞色素P450，家族成员1A1）活性的能力。
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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商品
Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.
抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子（如铁、铜和镉）引起的氧化损伤。
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