PHR1572

盐酸羟甲唑啉

certified reference material, pharmaceutical secondary standard

• 别名: 羟甲唑啉 盐酸盐, 2-（3-羟基-2,6-二甲基-4-叔丁基苄基）-2-咪唑啉 盐酸盐
• 经验公式（希尔记法）: C₁₆H₂₄N₂O · HCl
• CAS号: 2315-02-8
• 分子量: 296.84
• EC號碼: 219-015-0
• MDL號碼: MFCD00058147
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329823480
• NACRES: NA.24

属性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to Ph. Eur. O0290000; traceable to USP 1486004
• API 家族: oxymetazoline
• CofA: current certificate can be downloaded
• 包裝: pkg of 10 g
• 技術: HPLC: suitable; gas chromatography (GC): suitable
• 應用: pharmaceutical (small molecule)
• 格式: neat
• 儲存溫度: 2-30°C
• SMILES 字串: Cl.Cc1cc(c(O)c(C)c1CC2=NCCN2)C(C)(C)C
• InChI: 1S/C16H24N2O.ClH/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14;/h8,19H,6-7,9H2,1-5H3,(H,17,18);1H
• InChI 密鑰: BEEDODBODQVSIM-UHFFFAOYSA-N
• 基因資訊: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

说明

一般說明

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Oxymetazoline hydrochloride belongs to the category of non-selective adrenergic drugs commonly used as eye and nose drops.

應用

Oxymetazoline hydrochloride may be used as a pharmaceutical secondary standard for the determination of the analyte in pharmaceutical formulations using spectrophotometric technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化／生理作用

盐酸羟甲唑啉是一种部分 α_2A-肾上腺素受体激动剂；5-HT_1A、5-HT_1B 和 5-HT_1D 血清素受体的激动剂。它是 5-HT_1C 血清素受体的混合激动剂-拮抗剂。

腳註

To see an example of a Certificate of Analysis for this material enter LRAB5024 in the slot below. This is an example certificate only and may not be the lot that you receive.

推薦產品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

安全信息

• 象形圖: GHS06,GHS05
• 訊號詞: Danger
• 危險聲明: H300 + H330,H318,H412
• 防範說明: P260 - P264 - P273 - P280 - P304 + P340 + P310 - P305 + P351 + P338
• 危險分類: Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Aquatic Chronic 3 - Eye Dam. 1
• 儲存類別代碼: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• 水污染物質分類（WGK）: WGK 3