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Merck

N6522

Sigma-Aldrich

β-烟酰胺腺嘌呤二核苷酸 水合物

≥98%, BioUltra, from yeast

别名:

β-DPN, β-NAD, DPN, NAD, 二磷酸吡啶核苷酸, 辅酶, 辅酶 1, 辅酶 A

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About This Item

经验公式(希尔记法):
C21H27N7O14P2 · xH2O
CAS号:
分子量:
663.43 (anhydrous basis)
EC號碼:
MDL號碼:
分類程式碼代碼:
41106305
eCl@ss:
39200202
PubChem物質ID:
NACRES:
NA.55

生物源

yeast

品質等級

產品線

BioUltra

化驗

≥98%

形狀

powder

雜質

≤0.1% Insoluble matter

顏色

white to off-white

溶解度

H2O: 0.1 M, clear, colorless to faintly yellow

負離子痕跡

chloride (Cl-): ≤0.2%
sulfate (SO42-): ≤0.05%

正離子痕跡

Al: ≤0.0005%
Ca: ≤0.005%
Cu: ≤0.001%
Fe: ≤0.001%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

儲存溫度

−20°C

SMILES 字串

NC1=NC=NC2=C1N=CN2.O[C@@H]3[C@@H](COP(O)(OP(OC[C@@H](O4)[C@@H](O)[C@@H](O)[C@H]4[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)=O)OC[C@@H]3O

InChI

1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1

InChI 密鑰

BAWFJGJZGIEFAR-NNYOXOHSSA-N

基因資訊

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應用


  • Electrochemical Sensor Development: β-Nicotinamide adenine dinucleotide hydrate is utilized in the development of carbon nanomaterial-based electrochemical sensors and biosensors. These devices are designed for the sensitive detection of pharmaceutical and biological compounds, highlighting its crucial role in enhancing the sensitivity and specificity of biochemical assays (Adhikari et al., 2015).

生化/生理作用

电子受体

包裝

根据固体质量包装。

其他說明

本品是普通型 NAD。

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Ana P Gomes et al.
Cell, 155(7), 1624-1638 (2013-12-24)
Ever since eukaryotes subsumed the bacterial ancestor of mitochondria, the nuclear and mitochondrial genomes have had to closely coordinate their activities, as each encode different subunits of the oxidative phosphorylation (OXPHOS) system. Mitochondrial dysfunction is a hallmark of aging, but
Christian Dölle et al.
The FEBS journal, 280(15), 3530-3541 (2013-04-27)
Mitochondrial metabolism is intimately connected to the universal coenzyme NAD. In addition to its role in redox reactions of energy transduction, NAD serves as substrate in regulatory reactions that lead to its degradation. Importantly, all types of the known NAD-consuming
Jeerus Sucharitakul et al.
The Journal of biological chemistry, 288(49), 35210-35221 (2013-10-17)
3-Hydroxybenzoate 6-hydroxylase (3HB6H) from Rhodococcus jostii RHA1 is an NADH-specific flavoprotein monooxygenase that catalyzes the para-hydroxylation of 3-hydroxybenzoate (3HB) to form 2,5-dihydroxybenzoate (2,5-DHB). Based on results from stopped-flow spectrophotometry, the reduced enzyme-3HB complex reacts with oxygen to form a C4a-peroxy
Brian J North et al.
The EMBO journal, 33(13), 1438-1453 (2014-05-16)
Mice overexpressing the mitotic checkpoint kinase gene BubR1 live longer, whereas mice hypomorphic for BubR1 (BubR1(H/H)) live shorter and show signs of accelerated aging. As wild-type mice age, BubR1 levels decline in many tissues, a process that is proposed to
Gaëlle Laurent et al.
Molecular and cellular biology, 33(22), 4552-4561 (2013-09-18)
Sirtuins are a family of protein deacetylases, deacylases, and ADP-ribosyltransferases that regulate life span, control the onset of numerous age-associated diseases, and mediate metabolic homeostasis. We have uncovered a novel role for the mitochondrial sirtuin SIRT4 in the regulation of

实验方案

To measure alcohol dehydrogenase activity, this assay uses β-nicotinamide adenine dinucleotide phosphate and a continuous spectrophotometric rate determination at 340 nm.

在测定醇脱氢酶活性时,该测定使用β-烟酰胺腺嘌呤二核苷酸磷酸和在340nm处的连续分光光度法进行测定。

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