跳转至内容
Merck

C0166000

骨化二醇

European Pharmacopoeia (EP) Reference Standard

别名:

25-羟基维生素D3 一水合物, 25-羟基胆钙化醇

登录查看公司和协议定价


About This Item

经验公式(希尔记法):
C27H44O2 · H2O
CAS号:
分子量:
418.65
Beilstein:
4270041
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

生物源

sheep wool (grease)

等級

pharmaceutical primary standard

agency

EP

API 家族

calcifediol

形狀

solid

製造商/商標名

EDQM

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

pharmaceutical (small molecule)

形式

neat

SMILES 字串

[H][C@@]1(CC[C@@]2([H])C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C)[C@H](C)CCCC(C)(C)O

InChI

1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1

InChI 密鑰

JWUBBDSIWDLEOM-DTOXIADCSA-N

基因資訊

human ... VDR(7421)

正在寻找类似产品? 访问 产品对比指南

相关类别

一般說明

本品按现行药典规定交付。所有为支持本产品而提供的信息,包括SDS和任何产品信息单均由药典颁发机构制定并发布。如需更多信息和支持,请访问现行药典的网站。骨化二醇是维生素 D 的一种生物活性代谢物。由于对维生素D结合蛋白的高亲和力,与麦角钙化醇或胆钙化醇相比,它更具强的亲水性和更好的肠道吸收。众所周知该药物可治疗与肠道吸收减少和肥胖相关的疾病。

應用

骨化二醇EP 参考标准品设计用于欧洲药典规定的实验室测试。

包裝

本品按照现行药典要求提供。有关当前单位数量,请见EDQM 参考目录

其他說明

可能适用相应的销售限制。

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 文件 section.

如需帮助,请联系 客户支持

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Hypovitaminosis D: is it time to consider the use of calcifediol?
Cesareo R, et al.
Nutrients, 11(5), 1016-1016 (2019)
Kristyna Brabnikova-Maresova et al.
Arthritis research & therapy, 16(5), 460-460 (2014-10-05)
Juvenile idiopathic arthritis (JIA) is a disease associated with loss of bone mass, deterioration in bone mass quality and an increased risk of fractures. The objective of this study was to evaluate factors that predict bone mineral density (BMD) alterations
Johanna Breuer et al.
Annals of neurology, 75(5), 739-758 (2014-04-29)
Environmental conditions (eg, latitude) play a critical role in the susceptibility and severity of many autoimmune disorders, including multiple sclerosis (MS). Here, we investigated the mechanisms underlying the beneficial effects of immune regulatory processes induced in the skin by moderate
Fahim Abbasi et al.
The Journal of nutrition, 145(4), 714-719 (2015-03-06)
Individuals with prediabetes mellitus (PreDM) and low circulating 25-hydroxyvitamin D [25(OH)D] are at increased risk of type 2 diabetes mellitus (T2DM). We aimed to determine whether low 25(OH)D concentrations are associated with defects in insulin action and insulin secretion in
Cécile Meunier et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 989, 54-61 (2015-03-25)
Many methods for routine total plasma/serum 25-hydroxyvitamin D (25OHD) measurements are available from automated immunoassays to the most specific LC-MS/MS techniques. These last ones are nowadays numerous, still perfectible but more powerful than immunoassays in specific illnesses. We presented a

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门