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Merck

B1390

Supelco

比沙可啶

analytical standard, for drug analysis

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About This Item

经验公式(希尔记法):
C22H19NO4
CAS号:
分子量:
361.39
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

质量水平

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

forensics and toxicology
pharmaceutical (small molecule)
veterinary

包装形式

neat

储存温度

2-8°C

SMILES字符串

CC(=O)Oc1ccc(cc1)C(c2ccc(OC(C)=O)cc2)c3ccccn3

InChI

1S/C22H19NO4/c1-15(24)26-19-10-6-17(7-11-19)22(21-5-3-4-14-23-21)18-8-12-20(13-9-18)27-16(2)25/h3-14,22H,1-2H3

InChI key

KHOITXIGCFIULA-UHFFFAOYSA-N

基因信息

human ... CHRM4(1132)

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一般描述

Bisacodyl is a diphenylmethane derivative, mainly used as a stimulant laxative for treating constipation.

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Michael A Kamm et al.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 9(7), 577-583 (2011-03-29)
Although stimulant laxatives have been used for many years to treat patients with constipation, their clinical value has been questioned, and there have been few high-quality trials to assess their efficacy. We tested the efficacy and safety of 4 weeks
Mercedes Ibáñez et al.
Diseases of the colon and rectum, 54(12), 1578-1584 (2011-11-10)
No consensus exists regarding the optimal bowel preparation regimen for patients with poor bowel cleansing at a previous colonoscopy. We investigated the usefulness of an intensive cleansing regimen for repeat colonoscopy after previous failure of bowel preparation. A prospective observational
Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk (2011)
V Giorgio et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 25(1), 70-78 (2012-10-04)
Severe pediatric slow transit constipation (STC) is commonly due to intrinsic colonic neuromuscular disease. We sought to correlate neuromuscular histological phenotypes in pediatric STC with colonic manometric phenotypes using high-resolution manometry (HRM). We tested the hypothesis that failure of motor
Christian Friedrich et al.
Drug metabolism and pharmacokinetics, 26(5), 458-464 (2011-06-24)
The aim of this study was to determine whether administration of the prodrugs bisacodyl (Bisa) and sodium picosulfate (SPS) leads to excretion of their common active metabolite, bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM), in breast milk. Two groups of 8 healthy lactating women who

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