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Merck

91018

Supelco

(S)-NIFE

for chiral derivatization, ≥98.0%

别名:

N-(4-硝基苯氧基羰基)-L-苯基丙氨酸2-甲氧基乙酯

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About This Item

经验公式(希尔记法):
C19H20N2O7
分子量:
388.37
MDL编号:
UNSPSC代码:
12000000
PubChem化学物质编号:

等级

derivatization grade ((chiral))
for chiral derivatization

方案

≥98.0% (HPLC)
≥98.0%

表单

powder

SMILES字符串

COCCOC(=O)[C@H](Cc1ccccc1)NC(=O)Oc2ccc(cc2)[N+]([O-])=O

InChI

1S/C19H20N2O7/c1-26-11-12-27-18(22)17(13-14-5-3-2-4-6-14)20-19(23)28-16-9-7-15(8-10-16)21(24)25/h2-10,17H,11-13H2,1H3,(H,20,23)/t17-/m0/s1

InChI key

ZSOUYIBYVUBOGT-KRWDZBQOSA-N

其他说明

HPLC 分析氨基酸的新型手性衍生化试剂;仲氨基酸类的衍生化

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A. Peter et al.
Chromatographia, 52, 821-821 (2000)
E. Olajos et al.
Chromatographia, 54, 77-77 (2001)
Sonika Sethi et al.
Biomedical chromatography : BMC, 34(1), e4730-e4730 (2019-10-28)
LC separation of biologically and pharmaceutically important enantiomers (from racemic or non-racemic mixtures) remains a subject of importance. The present review article deals with the liquid chromatographic enantioseparation of chiral selective serotonin reuptake inhibitors (SSRIs), namely citalopram, paroxetine, sertraline and
Antal Péter et al.
Journal of chromatography. A, 948(1-2), 283-294 (2003-07-02)
A new chiral derivatizing agent, (S)-N-(4-nitrophenoxycarbonyl)phenylalanine methoxyethyl ester, (S)-NIFE, was applied for the high-performance liquid chromatographic separation of enantiomers of 19 unnatural secondary amino acids: proline, pipecolic acid analogues, piperazine-2-carboxylic acid, morpholine-3-carboxylic acid, thiomorpholine-3-carboxylic acid and analogues containing the 1,2,3,4-tetrahydroisoquinoline
Cecilia Barbas-Bernardos et al.
Journal of chromatography. A, 1611, 460598-460598 (2019-10-20)
In the nutrition field, there is a lack of understanding about the impact that dietary chiral composition may have on health, especially regarding cooked meals. Chiral amino acids (AAs) are naturally present in food and their proportion may vary quite

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