推荐产品
生物源
mouse
品質等級
共軛
unconjugated
抗體表格
ascites fluid
無性繁殖
monoclonal
物種活性
rabbit
製造商/商標名
Chemicon®
技術
ELISA: suitable
western blot: suitable
同型
IgG1κ
運輸包裝
wet ice
目標翻譯後修改
unmodified
一般說明
抗体分子通常包含与一对重链共价结合的两条免疫球蛋白轻链。免疫球蛋白轻链有两种类型,用希腊字母κ和λ表示。κ和γ轻链的长度约为250个氨基酸,平均质量约为25 kDa。在免疫球蛋白群体中发现的κ与λ的比例因物种而异。
特異性
与牛、山羊、亚美尼亚仓鼠、马、人、小鼠、大鼠和绵羊的交叉反应极小。
该抗体与天然一抗(主要与κ轻链)发生强烈反应。不适用于检测λ轻链。该抗体不与兔IgG的重链反应。该抗体已通过ELISA检测并吸附,以确保与牛、山羊、亚美尼亚仓鼠、马、人、小鼠、大鼠和绵羊免疫球蛋白的最小交叉反应。
免疫原
表位:κ轻链
采用兔IgG轻链制备。
應用
研究子类别
片段特异性二抗
片段特异性二抗
研究范畴
二抗&对照抗体
二抗&对照抗体
这种小鼠抗兔轻链抗体经验证可用于ELISA、WB法检测兔轻链。
標靶描述
25 kDa
外觀
腹水
通过色谱法从腹水中分离。溶液,溶于0.01M磷酸钠、0.25M NaCl中,pH 7.6。
儲存和穩定性
从收到之日起,在2°-8°C无菌条件下冷藏保存12个月。应避免反复冻/融循环。
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Neurobiology of aging, 75, 136-149 (2018-12-21)
β-Amyloid (Aβ) accumulation is an early event of Alzheimer's disease (AD) pathogenesis. Inhibition of Aβ production by β-secretase (BACE) has been proposed as a potential therapeutic strategy for AD. However, BACE inhibitors lack specificity and have had limited clinical benefit.
International journal of molecular sciences, 24(1) (2023-01-09)
The opioid peptide β-endorphin coexists in the pituitary and brain in its αN-acetylated form, which does not bind to opioid receptors. We now report that these neuropeptides exhibited opposite effects in in vivo paradigms, in which ligands of the sigma
The Journal of biological chemistry, 285(30), 23147-23158 (2010-05-25)
The processing and regulated secretion of IL-1beta are critical points of control of the biological activity of this important pro-inflammatory cytokine. IL-1beta is produced by both monocytes and macrophages, but the rate and mechanism of release differ according to the
The Journal of biological chemistry, 284(15), 9781-9787 (2009-02-12)
Synaptotagmin 2 (Syt2) functions as a low affinity, fast exocytic Ca(2+) sensor in neurons, where it is activated by Ca(2+) influx through voltage-gated channels. Targeted insertion of lacZ into the mouse syt2 locus reveals expression in mucin-secreting goblet cells of
Nature communications, 7, 12526-12526 (2016-08-25)
Crosslinking of B-cell receptor (BCR) sets off an apoptosis programme, but the underlying pathways remain obscure. Here we decipher the molecular mechanisms bridging B-cell activation and apoptosis mediated by post-translational modification (PTM). We find that O-GlcNAcase inhibition enhances B-cell activation
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门